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OverviewAn Introduction to Drug Synthesis explores the central role played by organic synthesis in the process of drug design and development. Written by an experienced and talented author to complement his existing An Introduction to Medicinal Chemistry, the book illustrates how organic synthesis makes important contributions throughout the drug design and discovery process - from the generation of novel drug structures to the improved efficiency of large scale synthesis. Avoiding excessively detailed descriptions of the underlying synthetic pathways, the book focuses on how synthesis can be used in a strategic way - how and why different synthetic approaches are adopted, and the pros and cons of each. With examples used extensively to illustrate the concepts presented, An Introduction to Drug Synthesis> is the ideal resource for any pharmaceutical or medicinal chemistry student who needs a thorough understanding of how the concepts of organic synthesis are applied to the development of therapeutic drugs. Online Resources An Introduction to Drug Synthesis is supported by online resources featuring: For registered adopters: - Figures from the book in electronic format; For students: - A suite of multiple-choice questions to support the learning process; - Additional case studies - More detailed descriptions of key synthetic reactions, as a source of further reference. Full Product DetailsAuthor: Graham L. Patrick (University of the West of Scotland)Publisher: Oxford University Press Imprint: Oxford University Press Dimensions: Width: 19.60cm , Height: 2.70cm , Length: 26.50cm Weight: 1.084kg ISBN: 9780198708438ISBN 10: 0198708432 Pages: 592 Publication Date: 15 January 2015 Audience: College/higher education , Undergraduate , Postgraduate, Research & Scholarly Format: Paperback Publisher's Status: Active Availability: To order Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us. Table of ContentsPART A: General synthetic principles1: The role of synthesis in drug discovery2: Drug synthesis3: Retrosynthesis4: Cyclic systems in drug synthesis5: The synthesis of chiral drugs6: Combinatorial and parallel synthesisPART B: Role of synthesis in the drug design and development process7: Synthesis of Lead Compounds8: Analogue Synthesis in Drug Design9: Synthesis of natural products and their analogues10: Chemical and process development11: Synthesis of isotopically labelled compoundsPART C: Synthesis of Selected Antibacterial Agents12: Tetracyclines13: Erythromycin and macrolide antibacterial agents14: Quinolones and fluoroquinolonesReviewsThe author has done a great job; it puts the context with the reaction, and fills a genuine gap in the market. Dr John Spencer, University of Sussex Author InformationGraham Patrick is a lecturer in Organic Chemistry and Medicinal Chemistry at the University of the West of Scotland, Glasgow. He is the author of four other undergraduate textbooks covering medicinal chemistry and organic chemistry, including Introduction to Medicinal Chemistry, which is now in its fifth edition. Tab Content 6Author Website:Countries AvailableAll regions |
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