Introduction to Biological and Small Molecule Drug Research and Development: Theory and Case Studies

Author:   C. Robin Ganellin ,  Roy Jefferis ,  Stanley M. Roberts
Publisher:   Elsevier Science Publishing Co Inc
ISBN:  

9780123971760


Pages:   472
Publication Date:   29 May 2013
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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Introduction to Biological and Small Molecule Drug Research and Development: Theory and Case Studies


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Author:   C. Robin Ganellin ,  Roy Jefferis ,  Stanley M. Roberts
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Elsevier Science Publishing Co Inc
Dimensions:   Width: 19.10cm , Height: 2.80cm , Length: 23.50cm
Weight:   1.120kg
ISBN:  

9780123971760


ISBN 10:   0123971764
Pages:   472
Publication Date:   29 May 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. 'Introduction to Enzymes, Receptors and Small Molecule Drugs' 2. Proteins: Structure and Function                                                                     3. The Drug Discovery Process – from Target Selection to Candidate              4. Introduction to Biopharmaceuticals                     5. Similarities and Differences in the Discovery, Development and Use of Biopharmaceuticals versus Small Molecule Drugs                                                                                           6. 'Approaching the Same...Treatment of Diabetes 7. The Structure and Business of Bio/pharmaceutical Companies including the Management of Risks and Resources 8. Gefitinib  9. Herceptin/T-DM1 10. Erythropoietin (Epogen/Eprex/NeoRecormon) 11. Lysosomal Storage diseases 12. Steroids for HRT 13. Anti-HIV protease inhibitor Darunavir  14. Anti-TNF Agents Remicade/Humira/Enbrel/Cimzia 15. The Cholesterol Lowering Drug - Ezetimibe

Reviews

From the perspective of the world's leading experts in the field of drug discovery, this book is the first to bridge the fundamental principles of drug discovery gained from developing small molecules with the newer approaches of developing peptide/protein biopharmaceuticals as therapeutic entities.I highly recommend this book to anyone who has a role in the drug discovery process. --Doody.com, October 4, 2013


"""Pharmacologists, pharmacists, and medical chemists review recent research and the current status of developing drugs from proteins, a practice that began with the advent of protein chemistry and genetic engineering during the 1990s.""--Reference & Research Book News, October 2013 ""From the perspective of the world's leading experts in the field of drug discovery, this book is the first to bridge the fundamental principles of drug discovery gained from developing small molecules with the newer approaches of developing peptide/protein biopharmaceuticals as therapeutic entities.I highly recommend this book to anyone who has a role in the drug discovery process.""--Doody.com, October 4, 2013"


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