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OverviewInterplay between Metal Ions and Nucleic Acids provides in an authoritative and timely manner in 12 stimulating chapters, written by 24 internationally recognized experts from 8 nations, and supported by nearly 1500 references, about 20 tables, and 125 illustrations, many in color, a most up-to-date view on metal ion-nucleic acid interactions; the characterization of which is covered in solution and in the solid state. The volume concentrates on modern developments encompassing topics in the wide range from G-quadruplexes via DNAzymes, catalysis at the DNA scaffold, and metal-mediated base pairs to peptide nucleic acids (PNAs) being thus of relevance, e.g., for chemistry and nanotechnology but also for molecular biology and (genetic) diagnostics. Full Product DetailsAuthor: Astrid Sigel , Helmut Sigel , Roland KO SigelPublisher: Springer Imprint: Springer Edition: 2012 Volume: 10 Dimensions: Width: 15.50cm , Height: 2.50cm , Length: 23.50cm Weight: 0.750kg ISBN: 9789400721715ISBN 10: 9400721714 Pages: 354 Publication Date: 03 January 2012 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Awaiting stock The supplier is currently out of stock of this item. It will be ordered for you and placed on backorder. Once it does come back in stock, we will ship it out for you. Table of Contents1. Characterization of Metal Ion-Nucleic Acid Interactions in Solution. - 2. Nucleic Acid-Metal Ion Interactions in the Solid State. - 3. Metal Ion-Promoted Conformational Changes of Oligonucleotides. - 4. G-Quadruplexes and Metal Ions. - 5. Metal Ion-Mediated DNA-Protein Interactions. - 6. Spectroscopic Investigations of Lanthanide Ion Binding to Nucleic Acids. - 7. Oxidative DNA Damage Mediated by Transition Metal Ions and Their Complexes. - 8. Metal Ion-Dependent DNAzymes and Their Applications as Biosensors. - 9. Enantioselective Catalysis at the DNA Scaffold. - 10. Alternative DNA Base Pairing through Metal Coordination. - 11. Metal-Mediated Base Pairs in Nucleic Acids with Purine- and Pyrimidine-Derived Nucleosides. - 12. Metal Complex Derivatives of Peptide Nucleic Acids.ReviewsFrom the reviews: Bioinorganic chemistry is an exciting branch of chemistry with applications in new materials (including sensors and tissues), health (diagnosis and therapy), energy supplies (generation and storage), biological function, evolution, and beyond. The Sigel volumes are always a reliable way of keeping abreast of this rapidly expanding field. This one is no exception. ... This book is a good read and all bioinorganic chemists might wish it was on their shelves-not only for research, but as a resource for undergraduate teaching (Peter J. Sadler, Angewandte Chemie International Edition, Vol.51, 2012) From the reviews: The focus here is on metal ion-nucleic acid interactions, both in the solid state and in solution, on single nucleic acids themselves through to oligonucleotides, and high-molecular-weight DNA. ... This book is a good read and all bioinorganic chemists might wish it was on their shelves-not only for research, but as a resource for undergraduate teaching. (Peter J. Sadler, Angewandte Chemie International Edition, Vol. 51, 2012) From the reviews: Bioinorganic chemistry is an exciting branch of chemistry with applications in new materials (including sensors and tissues), health (diagnosis and therapy), energy supplies (generation and storage), biological function, evolution, and beyond. The Sigel volumes are always a reliable way of keeping abreast of this rapidly expanding field. This one is no exception. ... This book is a good read and all bioinorganic chemists might wish it was on their shelves-not only for research, but as a resource for undergraduate teaching (Peter J. Sadler, Angewandte Chemie International Edition, Vol.51, 2012) 'Interplay between Metal Ions and Nucleic Acids' ... is for the entire community of researchers interested in metal-nucleic acid interactions. Its contents are highly topical, as they cover numerous relevant areas of a research that faces rapid growth. Reading this volume is a 'must' for scientists active in this field, and the editors should be congratulated on the fine selection of chapters and authors. ... volume10 of MILS is among the very best books on this subject that have appeared in recent years! (Bernhard Lippert, InorganicaChimicaActa,Vol. 394, January, 2013) Author InformationTab Content 6Author Website:Countries AvailableAll regions |
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