Overview

This series of fascicles comprising an International Classification of Rodent Tumours provides information and guidelines especially adapted for international use in practical toxicologic pathology. This is expressed in particular in the conciise easy-to-use format of the narrative in all sections. Included in this classification are tumours and relevant pre-neoplastic lesions of the rate for all organ systems. Only lesions are considered for which histopathological slides are available or which have been documented with pictures in the literature. The goal of this classifcation is to harmonize and standardise the nomenclature and diagnostic criteria to be used worldwide for regulatory purposes. The complete range of organ systems inthe rat will be covered in ten fascicles. Each fascicle is divided into different, so-called data-sheets, each of which represents the essential information on a particular lesion. Each data-sheet is prepared in a standard layout, always starting on a new page with a header section. The descriptions of the diagonstic features comprise the main histopathological features of the specified lesion, in the form of a concise list. Most data-sheets include at least one typcial micorgraph, selected from among both spontaneous and induced lesions.

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