Overview

With contributions from the leading researchers in the field, this volume brings together the latest studies on insulin action and signal transduction to provide a state-of-the-art reference for graduate researchers and students in diabetes and endocrinology. Insulin Signaling: From Cultured Cells to Animal Models is a comprehensive study of the regulation of molecular events by insulin at a cellular level, utilizing experimental techniques ranging from molecular systems through phenotypic expression in transgenic and knockout models. Content includes structural aspects of the insulin teceptor and its downstream effectors, mutations in the insulin receptor gene, insulin receptor folding, and IRS protein structure.

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9781420024753

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