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Author:   Mohamed Mahmoud Zakaria El-Kassas, MD (Helwan University, Egypt)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Weight:   0.450kg
ISBN:  

9780443413636

ISBN 10:   0443413630
Pages:   338
Publication Date:   13 April 2026
Audience:   Professional and scholarly ,  College/higher education ,  Professional & Vocational ,  Postgraduate, Research & Scholarly
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Section 1. Direct-Acting Antivirals (DAAs) in Hepatitis C 1. Hepatitis C Virus Overview 2. HCV-Host Interactions: Virus specific factors, virus host related determinants, and Intracellular Signaling 3. Introduction to Direct-Acting Antivirals: Mechanisms of Action and different classes Section 2. Therapeutic Strategies and Clinical Applications of DAAs in managing HCV 4. Clinical Efficacy of different DAAs regimens 5. Safety and tolerability of different DAAs regimens 6. Benefits of treating HCV by DAAs beyond virological response 7. Current landscape and guidelines of DAAs treatment in general population 8. Individualized treatment approaches in various special patient populations Section 3. Challenges and Future Directions in DAA Therapy 9. Antiviral Resistance in Hepatitis C and DAA Therapy 10. DAA Therapy and hepatocellular carcinoma 11. Limitations and unmet needs in DAAs therapy 12. Emerging Therapeutic Strategies and Future Directions 13. Access to DAAs therapy, and role of DAAs in targeted HCV elimination

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Author Information

Mohamed El-Kassas, a distinguished figure in hepatology, held prestigious positions in global medical organizations such as IASL, AHPBCC, WGO, Global NASH Council, and SLMENA. He has also held administrative roles in EARTH and the Egyptian National Committee for the Control of Viral Hepatitis. With a PG Diploma in Clinical Research, he received awards and recognition for his research, including the Best Arab Researcher Prize in Natural Sciences. He has published over 200 peer-reviewed manuscripts and served on the editorial boards of journals like PLOS One, Frontiers, and JCTH. He also reviewed for over 70 international journals, contributing to the field of hepatology.

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