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Insect biochemistry and molecular genetics have become enormously important sciences. Molecular genetics of drosophila has paced mammalian genetics and has facilitated many advances in mammalian genetics. Moreover, many life-threatening diseases for man are now carried chiefly by insects and our increasing knowledge of the basic science of insects may help to control these diseases. There is no more important facet of insect science than insect hormones, the agents that allow for communication between cells and tissues. This volume updates important areas of this subject, namely: hormonal control of ecdysis; ecdysone receptors in agriculture and medicine; molecular structure of the receptor ligand binding site of ecdysone; a molecular genetic approach to the biosynthesis of the molting hormone; non-steroidal ecdysone agonists; molecular actions of juvenile hormone in drosophila, and insect neuropeptide receptors.

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9780127098739

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Trained in biochemistry at the University of Wisconsin, Madison, Dr. Litwack worked on enzymology and the effects of hormones on enzyme systems. Then he was a Postdoctoral Fellow of the National Foundation for Infantile Paralysis at the Biochemical Institute of the Sorbonne in Paris. Dr. Litwack's first position was as Assistant Professor of Biochemistry at Rutgers University in 1954. Six years later, he joined the University of Pennsylvania as associate professor and four years later went to the Fels Institute for Cancer Research and Molecular Biology, as full professor, eventually becoming Deputy Director of the Institute. In 1991, he accepted the Chair of Pharmacology at Thomas Jefferson University where he is also Deputy Director of the Jefferson Cancer Institute and Associate Director for Basic Science in the Jefferson Cancer Center. Dr. Litwack's work has been in the area of mechanisms of steroid receptor action involving especially the glucocorticoid and mineralocorticoid receptors, immunophi.

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