Overview

Inflammatory bowel diseases (IBDs) are characterized by chronic inflammation of the GIT, with two main clinical manifestations: Crohn's disease, whose pathogenesis involves any part of the gastrointestinal tract, and ulcerative colitis, in which inflammation is limited to the colon. This gastrointestinal tract inflammation leads to symptoms such as bleeding, abdominal pain, diarrhea, malnutrition, and increased intestinal permeability. Among the factors involved in the pathogenesis of these diseases, genetics, dysregulation in the intestinal microbiota, and environmental factors such as diet and physical inactivity stand out. Considering the severity of symptoms related to IBDs, alternative therapies have been sought to alleviate intestinal discomfort, and physical exercise, dietary interventions, and nutritional supplements can bring benefits, which include improving the composition of the microbiota, intestinal tract, and its antioxidant and anti-inflammatory action, which may implement a protective action on the permeability in the gastrointestinal tract. This Issue Reprint summarizes various papers published in the collection ""Inflammatory Bowel Disease (IBD): Clinical Diagnosis and Treatment"", which aims to provide an approach to the clinical diagnosis and treatment of IBDs. This Reprint includes papers dedicated to the clinical diagnosis of IBDs, physical exercise and nutrition in IBDs, microbiota and IBDs, and body composition in IBDs.

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