Overview

This book is intended to be more than a comprehensive compilation of reviews by individual authors on different aspects of inflammatory bowel diseases. It is intended that the individual chapters be components of a coherent, albeit detailed, story of the local and systemic pathophysiology of intestinal inflammation, with a well-reasoned series of management strategies. Our goal was not only to produce a standard reference text, but also to present research advances and current concepts of etiopathogenesis in the context of what is already known of the clinicopathologic features of these disorders. Our vision was to have a book that would blend recent advances in the basic and clinical sciences as they relate to inflammatory bowel disease. It is our hope that the book will illustrate the effectiveness of a team approach of basic scientists and clinician investigators in this field. The book will give the reader a glimpse of where the field is moving and an idea of likely research directions in the future. Of course, it is our personal wish that this book will stimulate ideas for future research.

Full Product Details

Author:   Stephan R. Targan ,  Fergus Shanahan ,  Loren C. Karp
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   Softcover reprint of the original 2nd ed. 2003
ISBN:  

9781402034176

ISBN 10:   1402034172
Pages:   903
Publication Date:   14 February 2004
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Preface. Section 1: The Laboratory Bench. 1. Introduction: Inflammatory Bowel Diseases: From Bench to Bedside; F. Shanahan, et al. 2. The Changing Faces of Crohn's Disease and Ulcerative Colitis; A. Ekbom. 3. Genetics of Inflammatory Bowel Disease; K.D. Taylor, J.I. Rotter, H. Yang. 4. Experimental Mouse Models of Inflammatory Bowel Disease: New Insights Into Pathogenic Mechanisms; C.O. Elson, C. T. Weaver. 5. The Normal Intestinal Mucosa - A State of `Controlled Inflammation'; C. Fiochi. 6. The Lymphocyte-Epithelial-Bacterial Interface; R. Hershberg, R. Blumberg. 7. The Mucosal Inflammatory Response. Cytokines and Chemokines; F. Cominelli, K. O. Arseneau, T. T. Pizarro; 8. Role of the Microcirculation in Chronic Gut Inflammation; M. B. Grisham, F. S. Laroux, D. N. Granger. 9. Remission, Relapse, Intestinal Healing and Repair; M. N. Goeke, D. Podolsky. 10. Antibodies in the Exploration of Inflammatory Bowel Disease Pathogenesis and Disease Stratification; J. Braun, O. Cohavy, M. Eggena. 11. Pathophysiology of Inflammatory Bowel Disease: The Effect of Inflammation on Intestinal Function ; S. M. Collins, K. Croitoru. 12. Systemic Consequences of Intestinal Inflammation; K. A. Papadakis, M.T. Abreu. Section II: The Bedside. 13. Understanding Symptoms and Signs in Inflammatory Bowel Disease; C. C. Cronin, F. Shanahan 14. Clinical Course and Complications of Ulcerative Colitis and Ulcerative Proctitis; R. Panaccione, L. R. Sutherland. 15. Clinical Features and Complications of Crohn's Disease; W. J. Tremaine. 16. Mechanisms of Systemic Inflammation Associated With Intestinal Injury; R. B. Sartor. S. N. Lichtman 17. Pathology of Inflammatory Bowel Diseases: A Critical Appraisal in Diagnosis and Management; G. Cortina, K. Lewin. 18. An Endoscopic and Histologic Perspective of Diagnosis: When, Where and What to Do; C. N. Bernstein, R. H. Riddell. 19. Radiologic (Radiographic) and Imaging Features of Ulcerative Colitis and Crohn's Disease; E. Fitzgerald. 20. New Diagnostic Approaches; L. Kam, E. Vasiliauskas. 21. Differential Diagnosis of Colitis; S. C. Eng, C. M. Surawicz. 22. 'Disease Management' in Chronic Medical Conditions; D. H. Alpers. 23. Pharmacoeconomic and Inflammatory Bowel Disease; B. G. Feagan. 24. Measuring Quality of Life in Inflammatory Bowel Disease; E.J. Irvine. 25 Additional Chapters. Section III: Back to the Laboratory Bench. 50. Epilogue: Bench to Bedside and Back to Bench; S.R. Targan, L. C. Karp, F. Shanahan. Index.

Reviews

`This is one of the most comprehensive, well written and convincing books on IBD we have had the opportunity to examine in recent years. It is well written (it includes several well known experts in the field), nicely illustrated, up to date (references reach up to 2001) and extremely stimulating. If you have EUR 200 to invest, do not hesitate to buy this book: you will be well rewarded by all you will learn when you glance through its pages.' Digestive and Liver Disease, 36 (2004)

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