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OverviewThis book, the first of its kind in this subject area, will focus on in vitro approaches to the study of the toxicology of polluting agents (including heavy metals, radionuclides, micro-organics, estrogenic compounds, and complex mixtures) in the aquatic environment. The importance of in vitro methods is that they allow standardised techniques to be developed and validated for substance and species specific experiments in a controlled way. Also, they allow mechanistic studies without the problems of individual variation between animals and environmental stress. Full Product DetailsAuthor: Carmel Mothersill , Brian AustinPublisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K Edition: Softcover reprint of hardcover 1st ed. 2003 Dimensions: Width: 15.50cm , Height: 2.60cm , Length: 23.50cm Weight: 0.967kg ISBN: 9783642056963ISBN 10: 3642056962 Pages: 472 Publication Date: 04 December 2010 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: In Print This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsIntroduction; basic culture methods for aquatic species; basic approaches in in vitro toxicology; specialised tissue culture methods; Species specific techniques; endpoints and tools; recombinant technologies, proteomics and genomics, heavy metals; micro-organis and estrogenic compounds; carcinogens and genotoxic agents; radionuclides; sediments; biotoxins; validation: in vitro in vivo bridging approaches; regulation: practical and legal issues; discussionReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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