In Situ Molecular Pathology and Co-Expression Analyses

Author:   Gerard J. Nuovo (Ohio State University Medical Center, Columbus, OH, USA)
Publisher:   Elsevier Science Publishing Co Inc
ISBN:  

9780124159440


Pages:   298
Publication Date:   28 March 2013
Replaced By:   9780128206539
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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In Situ Molecular Pathology and Co-Expression Analyses


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Overview

In Situ Molecular Pathology and Co-Expression Analyses explains, in easy-to-understand language, simplified ways of understanding and performing in situ hybridization and immunohistochemistry tests. The book also focuses on straightforward protocols used to simultaneously detect two or more proteins/nucleic acids within intact tissue by doing co-expression analyses. The fields of in situ hybridization and immunohistochemistry have expanded rapidly due to the use of computer-based analysis. To get the most out of these automated platforms, researchers and diagnostic biomedical investigators must have a solid understanding of the basics of in situ-based tests, protocols, and regimens for troubleshooting. Practicing molecular pathologists, clinical chemists, and toxicologists, as well as clinicians and researchers in training, will benefit from this book's clear presentation of protocols and theoretical framework.

Full Product Details

Author:   Gerard J. Nuovo (Ohio State University Medical Center, Columbus, OH, USA)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Dimensions:   Width: 21.60cm , Height: 2.00cm , Length: 27.60cm
Weight:   1.210kg
ISBN:  

9780124159440


ISBN 10:   0124159443
Pages:   298
Publication Date:   28 March 2013
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Replaced By:   9780128206539
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. Introduction 2. The Basics of Molecular Pathology 3. The Biochemical Basis of In Situ Hybridization and Immunohistochemistry 4. The Basics of In Situ Hybridization 5. The Basics of Immunohistochemistry 6. The Basics of Histologic Interpretations of Tissues 7. The Recommended Protocol for In Situ Hybridization 8. The Recommended Protocol for Immunohistochemistry 9. Co-expression Analyses 10. PCR In Situ Hybridization and RT In Situ PCR

Reviews

Nuovo presents a textbook on in-situ-based molecular pathology for readers with minimum prior knowledge of molecular pathology in general and in-situ-based molecular pathology in particular. --Reference and Research Book News, August 2013


Author Information

Dr. Gerard Nuovo received his MD from the University of Vermont College of Medicine in 1983. He did his training in Anatomic Pathology at Columbia Prebyterian College of Physicians and Surgeons in NYC. He then did a two year fellowship at Columbia Presbyterian in Molecular Virology and Gynecologic Pathology under the mentorship of Drs. Saul Silverstein, Chris Crum, and Ralph Richart. Dr. Nuovo’s career has been dedicated to bridging the areas of surgical pathology and molecular pathology. He has published over 400 peer review papers in the field and written several textbooks in both Anatomic Pathology and Molecular Pathology. This textbook fulfills a strong ambition of Dr. Nuovo; to empower the next generation of researchers and diagnosticians to include in situ molecular pathology in their work by using easy-to-follow and easy-to-understand protocols for in situ hybridization, immunohistochemistry, and co-expression analyses.

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