Immunotoxicology and Risk Assessment

Author:   Dennis K. Flaherty
Publisher:   Springer Science+Business Media
Edition:   1999 ed.
ISBN:  

9780306459719


Pages:   382
Publication Date:   31 May 1999
Format:   Hardback
Availability:   In Print   Availability explained
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Immunotoxicology and Risk Assessment


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Overview

This work presents basic immunological tenets and mechanisms at the cellular and molecular level while employing the toxicology focus on hazard identification, appropriate assays, dose response, and risk assesment by mathematical models and safety factors. It will be a useful reference to toxicologists because it incorporates the 1999 EPA guidelines for all chemicals regulated under the Federal Insecticide, Fungicide, and Rodenticide Act and the Toxic Substances Control Act. Regulatory sections in each chapter focus on data from both the US Food and Drug Administration, as well as data applicable to western European Nations.

Full Product Details

Author:   Dennis K. Flaherty
Publisher:   Springer Science+Business Media
Imprint:   Kluwer Academic/Plenum Publishers
Edition:   1999 ed.
Dimensions:   Width: 15.50cm , Height: 2.50cm , Length: 23.50cm
Weight:   1.650kg
ISBN:  

9780306459719


ISBN 10:   030645971
Pages:   382
Publication Date:   31 May 1999
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

to Immunotoxicology.- Innate Immunity.- Cells of the Immune System.- Immunogenicity and Antigenicity.- Antigen-Presenting Cells.- Antigen Presentation.- Surface Interactions and Intracellular Signaling.- B-Cell Activation.- Antibodies.- Immunological Memory.- Complement.- Phagocytosis and Intracellular Killing.- Immediate Hypersensitivity Reactions.- Autoimmunity.- Delayed Hypersensitivity Reactions.- Killer Cells.- Killer Cells and Viral Infections.- Transplantation.- The Kines.- Assessment of Biological Significance.- Risk Characterization.- References.

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