Immunosenescence
Author:   Andreas Thiel
Publisher:   Springer Basel
Edition:   2012 ed.
ISBN:  

9783034807784


Pages:   238
Publication Date:   13 April 2014
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Immunosenescence


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Overview

As individuals age, their ability to respond to and clear pathogens and to control unwanted immune reactions declines, leading to a greater incidence of certain infectious diseases, autoimmunity and general immune dysfunctions. Most remarkably, the efficacy of vaccines is frequently decreased in elderly persons. Therefore, age-associated dysfunctions of the humoral and cellular immune responses have a strong clinical impact. Improving our understanding of the aged immune system is crucial in developing effective prevention and treatment programs that will facilitate healthy aging and improve the quality of life of the elderly population. The aim of this volume is to summarize current knowledge on the cellular and molecular aspects of the aging immune system, with an emphasis on infectious diseases and new therapeutic approaches.

Full Product Details

Author:   Andreas Thiel
Publisher:   Springer Basel
Imprint:   Springer Basel
Edition:   2012 ed.
Dimensions:   Width: 15.50cm , Height: 1.50cm , Length: 23.50cm
Weight:   0.397kg
ISBN:  

9783034807784


ISBN 10:   3034807783
Pages:   238
Publication Date:   13 April 2014
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.
Language:   English

Table of Contents

Regulation of Adaptive Immunity in the Elderly.- Does Innate Immunity Get Old?.- Thy(-Im)Munosenescence: The Ageing of the Thymus and Its Impact on the Immune System.- Characteristics of B Cells and B Cell Responses in Aged Individuals.- Mechanisms of Immune Protection to Pneumococcal Infection in the Young and the Elderly.- CMV Subversion of the Immune System in Later Life.- Aging and Autoimmunity.- Vaccination in the Elderly.- Immunosenescence and the 3r’s; Restoration, Replacement and Reprogramming.- Novel Strategies of Improved Vaccines for Elderly: The Example of Influenza.

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