Overview

Diseases of the gastrointestinal tract are common. There is increasing appreciation of the importance of the immune system in the pathogenesis of a number of these diseases. This book covers basic aspects of innate and adaptive immunity in the gastrointestinal tract, oral tolerance, and cellular and molecular mechanisms of acute and chronic inflammation. Specific disease covered include bacterial infections, human immunodeficiency virus (HIV) infection, coeliac disease, and inflammatory bowel disease. Other topics include mucosal immunisation and intestinal transplantation immunology. The readership of this book includes clinicians, scientists, and students interested in the gastrointestinal tract.

Full Product Details

Author:   Y.R. Mahida
Publisher:   Springer
Imprint:   Springer
Edition:   Softcover reprint of the original 1st ed. 2001
Volume:   31
Dimensions:   Width: 16.00cm , Height: 2.00cm , Length: 24.00cm
Weight:   0.602kg
ISBN:  

9789401038522

ISBN 10:   940103852
Pages:   359
Publication Date:   03 October 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

1. Intestinal mucosal innate immunity.- 2. Adaptive immunity in the gastrointestinal tract.- 3. Role of epithelial cells in mucosal immunobiology.- 4. Molecular immunology of mucosal T cells.- 5. Bacterial virulence mechanisms and the host immune response to enteric infection.- 6. HIV Infection of the gastrointestinal tract.- 7. Immunological aspects of Helicobacter pylori infection.- 8. Molecular pathogenesis and clinical immmunology of coeliac disease.- 9. Immunopathophysiology of inflammatory bowel disease.- 10. Rodent models of chronic intestinal inflammation.- 11. Regulation of intestinal immune responses to local antigens: oral tolerance vs immunopathology.- 12. Mucosal immunisation and vaccines.- 13. Transplantation immunology and the gut.

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Author Information

Yashwant Madida is a Professor in Medicine and Consultant Physician/Gastroenterologist at the University of Nottingham and University Hospital, Queen's Medical Centre in Nottingham. He obtained his medical qualification from the University of Liverpool and has worked in London, Oxford, and Boston (USA). His main areas of interest are inflammatory disease of the gastrointestinal tract and cellular and molecular aspects of host-microbial interactions.

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