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Immuno-oncology and immunotherapy Part B

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Author:   Lorenzo Galluzzi (Assistant Professor of Cell Biology in Radiation Oncology, Department of Radiation Oncology, Weill Cornell Medical College, NY, USA) ,  Norma Bloy (Weill Cornell Medical College, USA) ,  Maud Charpentier (Weill Cornell Medicine, USA)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Weight:   0.520kg
ISBN:  

9780443296161

ISBN 10:   0443296162
Pages:   236
Publication Date:   13 November 2024
Audience:   Professional and scholarly ,  College/higher education ,  Professional & Vocational ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

1. Multiparametric flow cytometry study of human MDSCs Luis de la Cruz-Merino and Victor Sanchez-Margalet Sr. 2. In vitro screening methods of novel immune checkpoint inhibitors related to T cell infiltration and anti-PD-1 resistance Yanfeng Gao, Zhuouying He, Xiuman Zhou and Youmei Xiao 3. Machine learning approach to assess brain metastatic burden in preclinical models Romina Goldszmid 4. Cytofluorometric analysis of the maturation and activation of bone marrow-derived dendritic cells to assess immunogenic cell death Dmitri Krysko, Faye Naessens, Iuliia Efimova and Mariia Saviuk 5. 3D agar colony inhibition assays to functionally evaluate HER2-targeting antibodies against human cancer cells elicited by vaccination in mice Pier-Luigi Lollini, Francesca Ruzzi, Maria Sofia Semprini, Laura Scalambra, Stefania Angelicola, Chiara Cappello, Olga Maria Pittino, Patrizia Nanni and Arianna Palladini 6. Spatial immunophenotyping of FFPE tissues by imaging mass cytometry Barbara Maier 7. Processing human colon cancer specimens for in vitro cytotoxicity assays Sofia Mensurado Santos, Rafael Blanco Domínguez, Bruno Silva-Santos, Mariana Carreira and Leandro Barros 8. A xenograft model of metastatic colon cancer Sofia Mensurado Santos and Rafael Blanco Domínguez 9. A preclinical model of hepatic metastasis to instruct effetive treatment modalities Anna Mondino, Citro Antonio, Lorenzo Piemonti, Arianna Pocaterra, Chiara Gnasso, Tamara Canu, Anna Tosi, Antonio Rosato and Antonio Esposito 10. Myeloid-derived suppressor cells: Identification and function Lorenzo Moretta, Nicola Tumino, Maria Teresa Bilotta and Paola Vacca 11. Measuring the impact of therapy-induced senescence on NK cell phenotypes in cancer Marcus Ruscetti, Shreya Chowdhury, Katherine Murphy, Chaitanya Parikh, Kelly DeMarco and Lin Zhou 12. Selective expansion of anti-tumour innate lymphocytes in long-term cultures after a single BCG pulse Mar Vales-Gomez

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Author Information

Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome “La Sapienza”. Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology. Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals: OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience. Norma received her master’s degree in health biology from Paris Saclay. In 2013, she joined the laboratory of Dr. Guido Kroemer at the Centre de Recherche des Cordeliers (Paris, France) and at Gustave Roussy (Villejuif, France), the largest center for oncological patients in Europe. She worked on several projects linked to immunosurveillance, culminating with her obtaining her PhD in 2017 with an original work on “Immunogenic stress and death of cancer cells: Contribution of antigenicity vs adjuvanticity to immunosurveillance”. She then moved to Weill Cornell Medicine to join the program in radiation and immunity under the mentorship of Dr. Galluzzi. Her current research is focused on investigating resistance to immunotherapy in a mouse model of HR+ breast cancer. Maud Charpentier received her M.Sc. in Cellular Biology and her Ph.D. in Immunology from the University of Nantes, France. She chose to pursue an academic career and continued her postdoctoral training in the United States. She joined the Department of Radiation Oncology at Weill Cornell Medicine under the mentorship of Dr. Sandra Demaria. Maud has a long-standing interest in the anti-tumor immune response and its role in controlling cancer progression and treatment outcomes. Her research focuses on understanding the synergy between radiation therapy and immunotherapy in solid tumors, with the aim of overcoming resistance to treatment and developing innovative therapeutic approaches in preclinical models.

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