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OverviewThe book is dedicated to the topical area of biology and medicine and the role of stress proteins HSP70 in the regulation of intracellular protein homeostasis, signaling transduction and cell protection. The book is divided into chapters, which describe the discovery of HSP70 and its molecular structure, the mechanism of the synthesis and function in normal and damaged cells, examine the role of HSP70 in immunity, cancerogenesis, aging, Alzheimer's disease and cardiac surgery. In this book, the author looks at HSP70 as a factor which prevents the transformation of homeostasis mechanisms of intracellular proteins into a link in the pathogenesis of a disease. Full Product DetailsAuthor: Igor MalyshevPublisher: Springer Imprint: Springer Edition: 2013 ed. Volume: 6 Dimensions: Width: 15.50cm , Height: 1.30cm , Length: 23.50cm Weight: 2.467kg ISBN: 9789400759428ISBN 10: 9400759428 Pages: 141 Publication Date: 08 January 2013 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand ![]() We will order this item for you from a manufactured on demand supplier. Table of ContentsAuthor's Foreword.- Introduction.- Chapter 1 A General Description of HSPs, the Molecular Structure of HSP70 and the HSP70 Cycle.- Chapter 2 The Functions of HSP70 in Normal Cells.- Chapter 3 HSP70 in Damaged Cells.- Chapter 4 Mechanisms of Activation and Inactivation of HSP70.- Synthesis.- Chapter 5 HSP70 in the Immune Responses.- Chapter 6 HSP70 in Carcinogenesis.- Chapter 7 HSP70 in Aging.- Chapter 8 The Role of HSP70 in the Protection of: (a) the Brain in Alzheimer's Disease, and (b) of the Heart in Cardiac Surgery. Index.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |