Overview

Immune-mediated inflammatory diseases (IMIDs) characterized by three nosological entities, autoimmune diseases, autoinflammatory diseases and inflammatory diseases of undetermined mechanism. Affections that constitute IMIDs are characterized by chronic inflammatory processes. All these affections are classified based on their immunogenetic, pathophysiological, and clinical profiles. It is well understood that similar therapeutic targets as well as prevention and treatment strategies can be developed for IMIDs with the same immunogenetic, pathophysiological, and clinical profiles. Admittedly, epidemiological and clinical studies of IMIDs are mostly partial and non-exhaustive, and have been conducted here and there in order to better understand the scope of this problem. However, there is no study that has explored IMIDs globally and exhaustsively, taking into account this immunogenetic, pathophysiological, and clinical classification. This work presents a comprehensive hospital-based study on IMIDs and an immunogenetic, pathophysiological, and clinical classification, now especially integrating epidemiological data (rare =1/2000).

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