Overview

This book offers a detailed review of the pathological and imaging features, diagnosis and treatment of IgG4-Related Kidney Disease (IgG4-RKD). IgG4-related disease (IgG4-RD), which is characterized by an elevated serum IgG4 level and infiltration of systemic organs by IgG4 positive plasma cells, is a newly recognized systemic disease. Diverse renal manifestations including specific tubulointerstitial nephritis, membranous nephropathy, and tumor-like urological diseases extending to the pelvis and urinary tract in IgG4-RD have been reported and are recently attracting attention as IgG4-RKD. In this book, leading researchers in the field present the latest insights into the broad spectrum of IgG4-RKD characteristics. In addition, they provide a detailed explanation of the pathology of IgG4-RKD including comparisons between the kidney and other affected organs, such as the lacrimal, salivary glands and pancreas in the histopathological section. IgG4-Related Kidney Disease will have a major impact on future immunological and nephrological studies and offers a useful resource not only for nephrologists but also general physicians and investigators in related fields.

Full Product Details

Author:   Takao Saito ,  John H. Stone ,  Hitoshi Nakashima ,  Takako Saeki
Publisher:   Springer Verlag, Japan
Imprint:   Springer Verlag, Japan
Edition:   Softcover reprint of the original 1st ed. 2016
Weight:   0.670kg
ISBN:  

9784431566762

ISBN 10:   4431566767
Pages:   311
Publication Date:   30 April 2018
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Part I. General Remarks.-1. IgG4-Related Disease: History and Overview.-2. IgG4-Related Disease: Pathological Features and Differential Diagnosis.-3. Potential Pathways in The Pathogenesis of IgG4-Related Disease.- 4. Does IgG4-Related Disease Have an Autoimmune Basis?.-5. Plasmablasts: A Promising Biomarker in IgG4-RD.-Part II. Features of IgG4-Related Ridney Disease and Associated Conditions.-6. Overview of IgG4-Related Kidney Disease.-7. IgG4-Related Kidney Disease: Clinical and Laboratory Features.-8. Imaging Findings.- 9. Characteristic Tubulointerstitial Nephritis in IgG4-Related Kidney Disease.-10. Electron Microscopic Findings.-11. IgG4-RelatedKidney Disease: Pathological Features –Membranous Glomerulonephritis.-12. IgG4-RelatedKidney Disease: Pathological Features –Other Glomerular Disease.-13. IgG4-Related kKidneyDiseases and Conditions: Renal Pelvic and Ureteral Diseases.-14. Retroperitoneal Fibrosis/Periaortitis and Hydronephrosis.-15. Other Urogenital Lesions (Testis, Paratesticular Lesion, Bladder, Prostate etc.).-16. Characteristic Distribution of Inflammatory Lesions in IgG4-Related Kidney Disease: Findings from Autopsy Case Series.-17. Diagnosis of IgG4-Related Kidney Disease.-18. Pathogenesis of IgG4-Related Kidney Disease.-Part III. Treatment of IgG4-RD and IgG4-RKD.-19. Corticosteroid Therapy for IgG4-Related Kidney Disease.-20. Targeting the B Cell Lineage in IgG4-Related Disease.-Part IV. Differential Diagnosis of IgG4-RKD.-21. Differential Diagnosis of IgG4-Related Tubulointerstitial Nephritis –An Overview.-22. Differential Diagnosis (1): ANCA Associated Vasculitis.-23. Differential Diagnosis (2): Castleman Disease.-24. Differential Diagnosis (3): Sjögren Syndrome.-25. Differential Diagnosis: Lupus Nephritis and IgG4-Related Kidney Disease.-Part V. Lessons from Cases.- 26. Multicentric Castleman’s Disease Mimicking IgG4-Related Disease; A Case Report.-27. A Case of Concurrent IgG4-Related Kidney Disease and Lupus Nephritis.

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Author Information

Takao Saito, Emeritus Professor, Faculty of Medicine, Fukuoka UniversityJohn H. Stone, Massachusetts General Hospital Hitoshi Nakashima, Division of Nephrology & Rheumatology, Department of Internal Medicine, Fukuoka University Takako Saeki, Department of Internal Medicine, Nagaoka Red Cross Hospital Mitsuhiro Kawano, Division of Rheumatology, Department of Internal Medicine, Kanazawa University

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