Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS

Author:   Swapan Chowdhury (Director of DMPK, Takeda Pharmaceutical International Co., Cambridge, MA, USA)
Publisher:   Elsevier Science & Technology
Volume:   v. 6
ISBN:  

9780444517104


Pages:   354
Publication Date:   04 November 2005
Replaced By:   9780128200186
Format:   Hardback
Availability:   In Print   Availability explained
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

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Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS


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Author:   Swapan Chowdhury (Director of DMPK, Takeda Pharmaceutical International Co., Cambridge, MA, USA)
Publisher:   Elsevier Science & Technology
Imprint:   Elsevier Science Ltd
Volume:   v. 6
Dimensions:   Width: 16.50cm , Height: 2.00cm , Length: 24.00cm
Weight:   0.790kg
ISBN:  

9780444517104


ISBN 10:   0444517103
Pages:   354
Publication Date:   04 November 2005
Audience:   Professional and scholarly ,  Professional & Vocational
Replaced By:   9780128200186
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   In Print   Availability explained
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

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Dr. Chowdhury is currently a Director of DMPK at Takeda Pharmaceutical International Co. in Cambridge, MA, responsible for evaluating metabolism, toxicity, and potential for drug-drug interaction due to modulation of activities of metabolizing enzymes and transporters by compounds in discovery and development. Dr. Chowdhury obtained his Ph.D. from the University of Alberta in 1987. After spending a year and a half as a post-doctoral fellow at the University of Toronto, Dr. Chowdhury joined Rockefeller University as a Research Associate in the laboratory of Professor Brian Chait. At Rockefeller University, Dr. Chowdhury was involved in the early stage of the development of atmospheric pressure ionization (API) mass spectrometry. This early research on API led to the introduction of a novel API system for LC/MS. After leaving Rockefeller University, he worked on the applications of liquid chromatography/mass spectrometry techniques at several non-academic organizations, including at Schering-Plough Research Institute (SPRI), where he worked for fifteen years in the Department of Drug Metabolism and Pharmacokinetics. The focus of his research at SPRI was to investigate the biotransformation of drugs in support of drug discovery and development. He was involved with the development and registration of a number of pharmaceuticals including Temodar, Clarinex, Zetia, Noxafil, Nasonex/Asmanex, and Victrelis. Dr. Chowdhury is an author of nearly 100 original publications covering a broad area of drug metabolism and drug-drug interaction and analytical technologies to evaluate them.

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