Overview

This textbook uses a case-study approach to present the core principles of biochemistry and molecular biology in the context of human disease to students who will be involved in patient care. The 29 clinical cases have been carefully selected to cover key scientific concepts and some common, and other not so common, diseases. While the principal focus is on topics relating to metabolic disease, further subjects such as connective tissue disorders, neurological disorders, auto-inflammatory disorders, infective diseases, and cancer are also addressed. Each chapter provides a specific patient report that includes the natural history, pertinent clinical laboratory data, physical findings, subsequent diagnosis, and therapy. This is followed by a comprehensive discussion of the normal biochemical processes and reactions pertaining to the case, along with the pathophysiological mechanisms of the disease. Graphical diagrams are provided in each chapter for ease of comprehension.

Full Product Details

9789811329760

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Reviews

“I believe that the book will appeal more to clinicians, both young and experienced and to clinical researchers … . The chapters are of reasonable and correct length and the language used is good and clear. The diagrams too are easy to follow. … The book would serve well if used in conjunction with more detailed pathology and biochemistry texts with strong clinical relevance. It can serve the doctors … .” (Venkatachalam Lakshminarayanan, goodreads.com, April 16, 2019) “The book's emphasis is on its role and importance in ‘bench‐to‐bedside’ training of healthcare professionals with the hope that this approach will have wide appeal in many disciplines related to pathobiochemistry. … This unique book combines biochemistry with molecular biology and presents various disorders in a case study format. This is indeed a unique strategy to present complex information. I am quite confident that medical students, researchers, clinicians and other healthcare professionals will find this book very useful.” (Omer Iqbal, Doody's Book Reviews, 27 September, 2019)

“The book's emphasis is on its role and importance in ‘bench‐to‐bedside’ training of healthcare professionals with the hope that this approach will have wide appeal in many disciplines related to pathobiochemistry. … This unique book combines biochemistry with molecular biology and presents various disorders in a case study format. This is indeed a unique strategy to present complex information. I am quite confident that medical students, researchers, clinicians and other healthcare professionals will find this book very useful.” (Omer Iqbal, Doody's Book Reviews, 27 September, 2019)

The book's emphasis is on its role and importance in 'bench-to-bedside' training of healthcare professionals with the hope that this approach will have wide appeal in many disciplines related to pathobiochemistry. ... This unique book combines biochemistry with molecular biology and presents various disorders in a case study format. This is indeed a unique strategy to present complex information. I am quite confident that medical students, researchers, clinicians and other healthcare professionals will find this book very useful. (Omer Iqbal, Doody's Book Reviews, 27 September, 2019)

Author Information

Toshitaka Oohashi, Ph.D., Professor of Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan Hirokazu Tsukahara, M.D., Ph.D., Professor of Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan Francesco Ramirez, Ph.D., Professor of Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA Chad Barber, Ph.D., Assistant Professor of Biology: California Lutheran University, Thousand Oaks, CA 91360, USA Fumio Otsuka, M.D., Ph.D., Professor of Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan

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