Overview

Human Organs-on-a-Chip Technology focuses on technology advancement from “organ-on-a-chip”, “multi organs-on-a-chip”, and the newest stage of “human organs-on-a-chip."" Chapters investigate the design, simulation studies, device development, and application of microfluidic systems. In addition, they offer expert perspectives on the development of an alternative test system in the biological evaluation of drugs, cosmetics, chemicals, medical devices, and many others. Lastly, the book addresses issues related to the development of microfluidic devices and alternative test systems in biological and biomedical research.

Full Product Details

Author:   P.V. Mohanan, PhD (Scientist-G and Head, Toxicology Division, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Govt. of India, India)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Weight:   0.450kg
ISBN:  

9780443137822

ISBN 10:   044313782
Pages:   628
Publication Date:   18 June 2024
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

1. Basics of Microfluidics technology 2. The Physics and Engineering of Flow in Organ on a Chip Devices 3. Importance of Soft lithography 4. Development of microfluidic devices 5. Microfluidics based point of care devices 6. Microfluidics, Organs-on-a-chip and 3D printing 7.Microfluidic platforms: applications and challenges 8. Design and simulation study of Organ-on-a-chip 9. Primary Cell culture for Organ-on-a-chip 10. Vascularisation in organs-on-a-chip 11. Organ-on-a-chip in nanotechnology 12. Organs-on-a-chip in precision medicine 13. Foeto-placental organ-on-a-chip 14. Organs-on-a-chip in drug development 15. Organ-on-a-chip for multianalyte monitoring 16. Organ-on-a-chip for Blood-brain-barrier studies 17. Organs on a chip models for sensor 18. Innovative ‘organs-on-a-chip’ technology for marine drug development 19. Exposure-on-a-chip as a model for inhalation toxicology and pharmacology research 20. Brain-on-chip 21. Recent breakthrough in organ-on-a-chip 22. 3D printed microfluidic chips 23. 3D tissue and Organ-on-a-chip models 24. Vascularisation of organoids in microfluidic chips 25. Multiorgans-on-a-chip: Design and applications 26. Multiorgans-on-a-chip for subacute toxicity 27. Multiorgans-on-a-chip for acute toxicity 28. Human organs-on-a-chip for biological evaluation 29. Human organs-on-a-chip for cancer modelling

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Author Information

Dr. Mohanan FNASc, is the Head of the Division of Toxicology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (Govt. of India). He is a visiting professor and visiting researcher at Toyo University, Japan and a Certified Biological Safety Specialist. Previously, he was a JSPS Post doctoral Fellow at the University of Tsukuba, Japan in the field of Neurotoxicity. He joined Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Govt. of India in 1989 and has spent 33 years of professional life working there. As a toxicologist he has been intimately associated with all the medical devices/technologies developed at SCTIMST. He received the lifetime achievement award from the Society of Toxicology India, for the outstanding contribution in the field of toxicology. He also patented an ELISA kit for the measurement of pyrogenicity. Mohanan made significant contributions for the development of medical device regulations in India. He has authored 231 publications and edited 6 books. Presently he is the secretary general of the Society of Toxicology, India.

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