Overview
Whereas plant and insect infections are commonly caused by fungi, only a small minority of the vast diversity of fungal species is pathogenic to humans. Despite this, fungal infections cause considerable morbidity and mortality worldwide. This volume is dedicated to the biology, clinical presentation and management of invasive fungal infections. Major pathogenic fungi are introduced by world-leading experts and the basic principles of fungal virulence are reviewed in the light of new results and experimental technologies that offer unprecedented insights into invasive infections caused by Aspergillus, Candida, Cryptococcus, Pneumocystis and Mucorales. In parallel, the clinical presentation of invasive fungal infections and current approaches to their diagnosis and treatment are summarized to provide an overview of human pathogenic fungi, linking pathogen biology to the clinical presentation of disease.
Full Product Details
Author: Oliver Kurzai
Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition: 2nd ed. 2014
Volume: 12
Dimensions:
Width: 17.80cm
, Height: 1.70cm
, Length: 25.40cm
Weight: 6.033kg
ISBN: 9783662496046
ISBN 10: 3662496046
Pages: 298
Publication Date: 16 December 2013
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Paperback
Publisher's Status: Active
Availability: Manufactured on demand 
We will order this item for you from a manufactured on demand supplier.
Table of Contents
Basics of Fungal Virulence 1 From Commensal to Pathogen: Candida albicans A. Whittington, N.A.R. Gow, and B. Hube 2 Aspergillus fumigatus: Saprotroph to Pathogen E. Bignell 3 Systems Biology Approaches to Understand and Predict Fungal Virulence L. Tierney, K. Tyc, E. Klipp, and K. Kuchler Immune Response to Fungal Infections 4 Receptor-Ligand Interactions in Fungal Infections S.E. Hardison and G.D. Brown 5 Macrophages in the Immune Response against Cryptococcus R.J. Evans and R.C. May 6 T Cell Responses in Fungal Infections C. Cunha, F. Aversa, L. Romani and A. Carvalho 7 Molecular Mechanisms of Histoplasma Pathogenesis C.A. Rappleye 8 Visualizing Immune Responses in Fungal Infections – Established and Novel Methods M. Hasenberg, S. Krappmann and M. Gunzer 9 Mucosal Immunology in Candida albicans Infection G. Weindl, J.R. Naglik, D.L. Moyes, and M. Schaller Clinical Presentations and Epidemiology of Fungal Infections 10 Invasive Aspergillosis in the Intensive Care Unit W. Meersseman 11 Molecular Epidemiology of Pneumocystis Outbreaks P.M. Hauser and J.A. Kovacs 12 Infections Caused by Mucorales C.B. Moore and M.D. Richardson 13 Diagnostics of Fungal Infections B. Willinger, D. Kienzl, and O. Kurzai Treatment of Fungal Infections 14 Therapeutic Strategies in Fungal Infections M.J.G.T. Vehreschild, K. Wahlers and O.A. Cornely 15 Antifungal Pharmacokinetics F. Farowski and O.A. Cornely
Reviews
From the book reviews: The Editor is to be congratulated on largely achieving his aim of producing an inspiring work for the fungi of major medical concern, but dermatophytes and other opportunistic fungi do not feature as strongly as might be expected in such a title. ... this volume does approach that for the major human pathogens and should be accessible to both practising consultants and pathologists, as well as to researchers and those studying medical microbiology. (Ima Fungus, Vol. 5 (1), June, 2014)
From the book reviews: The Editor is to be congratulated on largely achieving his aim of producing an inspiring work for the fungi of major medical concern, but dermatophytes and other opportunistic fungi do not feature as strongly as might be expected in such a title. ... this volume does approach that for the major human pathogens and should be accessible to both practising consultants and pathologists, as well as to researchers and those studying medical microbiology. (Ima Fungus, Vol. 5 (1), June, 2014)
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