Overview

How did Seattle become home to some of the world's most influential infectious-diseases researchers? Hot Spot tells the story of young physician-scientists drawn to the ""off you go"" spirit of the Pacific Northwest. A University of Washington researcher discovered scores of new sexually transmitted pathogens and created a widely copied ""Seattle model"" to treat and prevent them. Another led clinical trials for the world's first antiviral therapy. Others found ways to protect immune-weakened patients from deadly infections after a bone marrow transplant. Such innovations put Seattle at the forefront of both the HIV/AIDS pandemic and the new field of global health. When COVID-19 emerged, Seattle was ready.

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Hot Spot captures the energy, intellectual curiosity, and collaborative spirit that marked me enormously during my time in Seattle. It brought back many memories of the larger-than-life personalities who inspired generations of scientists. -Peter Piot, former director, London School of Hygiene & Tropical Medicine; former executive director, UNAIDS.

Hot Spot captures the energy, intellectual curiosity, and collaborative spirit that marked me enormously during my time in Seattle. It brought back many memories of the larger-than-life personalities who inspired generations of scientists. -Peter Piot, former director, London School of Hygiene & Tropical Medicine; former executive director, UNAIDS.

Author Information

Mary Engel is an award-winning healthcare writer who has worked for newspapers in California, Alaska, and New Mexico and as a science writer for the Fred Hutchinson Cancer Research Center. The editorials she wrote for the Los Angeles Times were part of a 2005 Pulitzer Prize-winning series on mismanagement, malpractice, and racial injustice at a public hospital. She has been a Knight Science Journalism Fellow at MIT, a science journalism fellow at the Marine Biological Laboratory in Woods Hole, Mass., and a Salzburg Seminar Knight Media Fellow on multicultural healthcare in Salzburg, Austria. She lives in Seattle.

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