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OverviewSome investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of ""estrogen mimics"" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decisionmakers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occurs--in diet, in pharmaceuticals, from industrial releases into the environment--and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature.The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents. Full Product DetailsAuthor: National Research Council , Commission on Life Sciences , Board on Environmental Studies and Toxicology , Committee on Hormonally Active Agents in the EnvironmentPublisher: National Academies Press Imprint: National Academies Press Dimensions: Width: 15.20cm , Height: 3.40cm , Length: 22.90cm Weight: 0.875kg ISBN: 9780309064194ISBN 10: 0309064198 Pages: 452 Publication Date: 03 February 2000 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Out of stock The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available. Table of Contents1 Front Matter; 2 Executive Summary; 3 1 Introduction; 4 2 Hormonally Active Agents; 5 3 Exposures: Sources and Dynamics of Hormonally Active Agents in the Environment; 6 4 Dosimetry; 7 5 Effects on Reproduction and Development; 8 6 Neurologic Effects; 9 7 Immunologic Effects; 10 8 HAAs and Carcinogenesis in Animals; 11 9 HAAS and Carcinogenesis in Humans; 12 10 Ecologic Effects; 13 11 Screening and Monitoring; 14 References; 15 Appendix A: Reproductive Effects Caused by Deithylstilbesterol; 16 Appendix B: Biographical Information on the Committee on Hormonally Active Agents in the Environment; 17 Addendum: Endocrine Disruptor Screening and Testing Advisory Committee; 18 IndexReviewsAuthor InformationCommittee on Hormonally Active Agents in the Environment, National Research Council Tab Content 6Author Website:Countries AvailableAll regions |
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