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Author:   Sławomir Filipek
Publisher:   Springer-Verlag New York Inc.
Imprint:   Humana
Edition:   2023 ed.
Volume:   2627
ISBN:  

9781071629765

ISBN 10:   107162976
Pages:   376
Publication Date:   24 March 2023
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Homology Modeling in the Twilight Zone: Improved Accuracy by Sequence Space Analysis.- Illuminating the ‘Twilight Zone’: Advances in Difficult Protein Modeling.- Contact-Assisted Threading in Low-Homology Protein Modeling.- Omics and Remote Homology Integration to Decipher Protein Functionality.- Easy not Easy: Comparative Modeling with High Sequence Identity Templates.- Quality Estimates for 3D Protein Models.- Using Local Protein Model Quality Estimates to Guide a Molecular Dynamics Based Refinement Strategy.- Specificities of Modeling of Membrane Proteins Using Multi-Template Homology Modeling.- Homology Modeling of the G Protein-Coupled Receptors.- Modeling of Olfactory Receptors.- Analyses of Mutation Displacements from Homology Models.- Persistent Homology for RNA Data Analysis.- Computational Methods to Predict Intrinsically Disordered Regions and Functional Regions in Them.- Homology Modeling of Transporter Proteins.- Modeling of SARS-CoV-2 Virus Proteins: Implications on Its Proteome.- Homology Modeling of Antibody Variable Regions: Methods and Applications.- 3D-BMPP: 3D Beta-Barrel Membrane Protein Predictor.- Protein Homology Modeling for Effective Drug Design.- Specificities of Protein Homology Modeling for Allosteric Drug Design.- Modeling of Protein Complexes.

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