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Author:   Ming-Ming Zhou
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2015
Dimensions:   Width: 15.50cm , Height: 1.50cm , Length: 23.50cm
Weight:   4.453kg
ISBN:  

9783319376660

ISBN 10:   3319376667
Pages:   282
Publication Date:   17 October 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

The Bromodomain as the Acetyl-Lysine Binding Domain in Gene Transcription.- PHD Fingers as Histone Readers.- Methyl-Lysine Recognition by the Royal Family Modules: Chromo, Tudor, MBT, Chromo Barrel, and PWWP Domains.- Histone Recognition by WD40 Proteins.- Methyl-Lys Recognition by Ankyrin Repeat Proteins.- Methyl-Arginine Recognition by Tudor Domains.- Histone Recognition by Tandem Modules and Modulation by Multiple PTMs.- Genome-Wide Profiling of Molecular Recognition of Histone PTMs.- BET Bromodomain Inhibition as a Therapeutic Approach in Hematological Malignancies.- Anti-Inflammatory Effects of BET Protein Inhibition Through Modulation of Gene Transcription.- Activating Latent HIV by Inhibiting Bromodomain Proteins.- Small Molecule Modulation of Methyl-Lysine Mediated Interactions.

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