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Author:   Patrizio Blandina ,  Maria Beatrice Passani ,  Gustavo Provensi
Publisher:   Springer International Publishing AG
Imprint:   Humana
Edition:   Second Edition 2025
Volume:   2
ISBN:  

9783031989209

ISBN 10:   3031989201
Pages:   227
Publication Date:   27 September 2025
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Molecular aspects of histamine receptors.- Genetic polymorphisms in the histamine receptor family.- The role of the histamine H4 receptor in asthma and atopic dermatitis.- Identification and roles of zebrafish histamine receptors.- Histamine H3r antagonists: from scaffold hopping to clinical candidates.- Clinical significance of histamine H1 receptor gene expression and drug action of antihistamines.- Histamine and its receptors as a module of the biogenic amine diseasome.- Histaminergic regulation of blood-brain barrier activity.- Histamine function in nervous systems.- Heterogeneity of histaminergic neurons.- Modulation by histamine H3 receptors of neurotransmitter release in the basal ganglia.- Interaction of brain histaminergic and dopaminergic systems.- Histamine H1 Receptor Occupancy in Human Brain Measured by Positron Emission Tomography.- Modulation of memory consolidation and extinction by brain histamine.- Histamine and appetite.

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Author Information

Patrizio Blandina, MD, Professor, Department of Neurosciences, Psychology, Drug Research and Child Health (NEUROFARBA), University of Florence, Florence, Italy. Maria Beatrice Passani, PhD, Professor, Department of Health Sciences (DSS), University of Florence, Florence, Italy. Gustavo Provensi, PhD, Professor, Department of Neurosciences, Psychology, Drug Research and Child Health (NEUROFARBA), University of Florence, Florence, Italy.

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