High-Throughput Screening in Drug Discovery
Author:   Joerg Huser (Bayer HealthCare, Wuppertal, Germany) ,  Raimund Mannhold (University of Dusseldorf, Ge) ,  Hugo Kubinyi (University of Heidelberg, Germany) ,  Gerd Folkers (Swiss Institute of Technology (ETH), Zurich, Switze)
Publisher:   John Wiley and Sons Ltd
Volume:   35
ISBN:  

9783527609369


Pages:   362
Publication Date:   13 December 2006
Format:   Electronic book text
Availability:   Available To Order   Availability explained
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High-Throughput Screening in Drug Discovery


Overview

Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. Chapter authors from leading pharmaceutical companies as well as from Harvard University discuss such factors as chemical genetics, binding, cell-based and biochemical assays, the efficient use of compound libraries and data mining using cell-based assay results. For both academics and professionals in the pharma and biotech industries working on small molecule screening.

Full Product Details

Author:   Joerg Huser (Bayer HealthCare, Wuppertal, Germany) ,  Raimund Mannhold (University of Dusseldorf, Ge) ,  Hugo Kubinyi (University of Heidelberg, Germany) ,  Gerd Folkers (Swiss Institute of Technology (ETH), Zurich, Switze)
Publisher:   John Wiley and Sons Ltd
Imprint:   Wiley-VCH Verlag GmbH
Volume:   35
ISBN:  

9783527609369


ISBN 10:   3527609369
Pages:   362
Publication Date:   13 December 2006
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Electronic book text
Publisher's Status:   Active
Availability:   Available To Order   Availability explained
We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately.

Table of Contents

Chemical Genetics (C. Shamu, Harvard University) High-Throughput Screening for Targeted Drug Discovery (J. Huser, Bayer Healthcare) Laboratory Automation (J. Comley, Cambridge, UK) Cell-based Assays (J. Huser, Bayer HealthCare)) Biochemical Assays (W. Mallender, Millennium Pharmaceuticals) High-Content Screening (P. Lipp, University of Homburg/Saar) Handling and Management of Primary Assay Data (H. Gubler, Novartis Pharma) Chemoinformatic Tools for HTS Data Analysis (S. Mundt, Bayer HealthCare) Combinatorial Chemistry and High-throughput Screening (R.A. Smith and N. Griebenow, Bayer HealthCare) Data Mining Using Cell-Based Assay Results (J. Caldwell, Novartis Institute)

Reviews

.. .ein professioneller Leitfaden fur erfolgreiche Wirkstoff-Screenings, der sich an Forscher in Planung wie auch in laufenden Screenings richtet. Chemiereport.at


Author Information

Dr. Jorg Huser is Director of HTS Technologies at the Healthcare Division of Bayer AG in Wuppertal (Germany).

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