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Author:   Paul A. Johnston ,  Oscar J. Trask
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   2nd ed. 2018
Volume:   1683
Weight:   1.294kg
ISBN:  

9781493973552

ISBN 10:   149397355
Pages:   397
Publication Date:   30 October 2017
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Applications and Caveats on the Utilization of DNA-specific Probes in Cell-based Assays.- General Staining and Segmentation Procedures for High Content Imaging and Analysis.- Tools to Measure Cell Health and Cytotoxicity Using High Content Imaging and Analysis.- Cell-based High Content Analysis of Cell Proliferation and Apoptosis.- Tools to Measure Autophagy using High Content Imaging and Analysis.- Guidelines for Microplate Selection in High Content Imaging.- Quality Control for High-Throughput Imaging Experiments using Machine Learning in CellProfiler.- High Content Screening Approaches That Minimize Confounding Factors in RNAi, CRISPR and Small Molecule Screening.- Strategies and solutions to Maintain and Retain Data from High Content Imaging, Analysis, and Screening Assays.- Live-Cell High Content Screening in Drug Development.- Challenges and Opportunities in Enabling High-Throughput, Miniaturized High-Content Screening.- Translocation Biosensors - Versatile Tools to Probe ProteinFunctions In Living Cells.- High Content Positional Biosensor Assay to Screen for Compounds that Prevent or Disrupt Androgen Receptor and Transcription Intermediary Factor 2 Protein-Protein Interactions.- High Content Imaging Assays for IL-6-induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines.- Single Cell and Population Level Analysis of HCA Data.- Utilization of Multidimensional Data in the Analysis of Ultra High Throughput High Content Phenotypic Screens.- High Content Screening of Mammalian Primary Cortical Neurons.- Human Derived Neurons and Neural Progenitor Cells in High Content Imaging Applications.- Determination of Hepatotoxicity in iPSC-Derived Hepatocytes by Multiplexed High-Content Assays.- The Generation of Three-Dimensional Head and Neck Cancer Models for Drug Discovery in 384-well Ultra-Low Attachment Microplates.- An Endothelial Cell/Mesenchymal Stem Cell Co-Culture Cord Formation Assay to Model Vascular Biology In Vitro.- High-throughput Automated Chemical Screens in Zebrafish.

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