Overview

Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. The national annual incidence rate of colorectal cancer is approximately 148,000+, striking slightly more females than males. The lifetime risk of colorectal cancer is 5-6%, however patients with a familial risk (with two or more first or second degree relatives) make up 20% of the patients. Persons who carry genetic mutations linked to hereditary colorectal cancer are the most likely to develop the disease.

Full Product Details

Author:   Miguel A. Rodriguez-Bigas ,  Raul Cutait ,  Patrick M. Lynch ,  Ian Tomlinson
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2010 ed.
Volume:   5
Dimensions:   Width: 15.50cm , Height: 3.60cm , Length: 23.50cm
Weight:   0.979kg
ISBN:  

9781461426622

ISBN 10:   1461426626
Pages:   630
Publication Date:   07 November 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

History.- History: Familial Adenomatous Polyposis.- Historical Aspects of Lynch Syndrome.- Basic Sciences and Genetics.- Molecular Genetics of Familial Adenomatous Polyposis.- DNA Mismatch Repair.- Basic Sciences and Genetics: Hamartomatous Polyposis.- Hyperplastic Polyposis Syndrome: Colorectal Cancer Predisposition.- MUTYH-Associated Polyposis.- Polymorphic Variation and Risk of Colorectal Cancer.- Pathology.- The Pathologist and the Phenotype of Hereditary Colorectal Cancer.- Clinical Science: Familial Adenomatous Polyposis.- Genotype Phenotype Correlation in Familial Adenomatous Polyposis.- Surgery for Familial Adenomatous Polyposis.- Duodenal Adenomas in Familial Adenomatous Polyposis.- FAP-Associated Desmoid Tumours.- Attenuated Familial Adenomatous Polyposis: Diagnosis, Management, and Future Prognosis.- Clinical Science: Hereditary Nonpolyposis Colorectal Cancer.- An Overview of the Lynch Syndrome (Hereditary Non-polyposis Colorectal Cancer).- Surgical Management in Lynch Syndrome.- Extracolonic Tumors.- Surveillance.- Clinical Science: MYH Associated Polyposis.- MUTYH-Associated Polyposis.- Clinical Science: Hamartomatous Polyposis.- Peutz–Jeghers Syndrome.- Clinical Aspects of Juvenile Polyposis.- Hereditary Mixed Polyposis Syndrome and Multiple Adenoma Patients.- Clinical Science: Hyperplastics Polyposis.- Hyperplastic Polyposis.- Genetic Counseling.- Genetic Counseling Overview.- Across Culture and Health Systems: Europe.- Across Culture and Health Systems: Asia (Hong Kong).- Across Culture and Health Systems: Asia (Japan).- Across Culture and Health Systems: Africa.- Across Culture and Health Systems: Argentina.- Genetic Counselling Across Culture and Health Systems: Australia.- Across Culture and Health Systems: Korea.- Across Culture and Health Systems: America.- Psychosocial Aspects of Hereditary Colorectal Cancer.- Psychological Impact of Genetic Counseling and Testing for Hereditary Colorectal Cancers.- Chemoprevention.- Chemoprevention for Inherited Colorectal Cancer.- Registries.- Registries.- Erratum.- Erratumto: Chapter 22: Hereditary Mixed Polyposis Syndrome and Multiple Adenoma Patients.

Reviews

From the reviews: This comprehensive book details basic scientific knowledge, clinically relevant algorithms, and the historical framework of hereditary colorectal cancer. ... It is written for colorectal specialists, which may include surgeons, gastroenterologists, oncologists, and geneticists. ... The book would be an excellent definitive reference for any medical library. ... There is no comparable book, and the information it provides would be very difficult to obtain from other sources in such a well - balanced and complete presentation. (Neal Wilkinson, Doody's Review Service, January, 2011)

From the reviews: This comprehensive book details basic scientific knowledge, clinically relevant algorithms, and the historical framework of hereditary colorectal cancer. ... It is written for colorectal specialists, which may include surgeons, gastroenterologists, oncologists, and geneticists. ... The book would be an excellent definitive reference for any medical library. ... There is no comparable book, and the information it provides would be very difficult to obtain from other sources in such a well - balanced and complete presentation. (Neal Wilkinson, Doody's Review Service, January, 2011)

This unique book is designed as a consultative source for individuals involved in the care of patients with colorectal cancer and patients at risk due to familial genetic testing. ... Genetics counselors, medical geneticists, surgeons, and oncology specialists would find this book extremely useful. ... The intimidating subject of hereditary colorectal cancer is well reviewed and presented in an easy-to-read manner. A job well done. (Luis F. Escobar, Doody's Book Reviews, October, 2018) This comprehensive book details basic scientific knowledge, clinically relevant algorithms, and the historical framework of hereditary colorectal cancer. ... It is written for colorectal specialists, which may include surgeons, gastroenterologists, oncologists, and geneticists. ... The book would be an excellent definitive reference for any medical library. ... There is no comparable book, and the information it provides would be very difficult to obtain from other sources in such a well - balanced and complete presentation. (Neal Wilkinson, Doody's Review Service, January, 2011)

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