Hepatitis Delta Virus
Author:   John L. Casey
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Edition:   2006 ed.
Volume:   307
ISBN:  

9783540298014


Pages:   228
Publication Date:   09 May 2006
Format:   Hardback
Availability:   Out of stock   Availability explained
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Hepatitis Delta Virus


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Overview

Hepatitis delta virus which causes severe acute and chronic liver disease was discovered following the detection of a novel antigen-antibody system in hepatitis B virus carriers. Currently, HDV is classified as a subviral satellite of hepatitis B virus. However, unlike other satellite viruses, the dependence of HDV on HBV is limited solely to the provision of an envelope of hepatitis B surface antigen for virus assembly. Research into the molecular virology of the HDV life cycle has revealed a fascinating collection of biology. These insights are now beginning to be translated into new potential treatment strategies. There are currently still an estimated 15 million HDV carriers worldwide.

Full Product Details

Author:   John L. Casey
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   2006 ed.
Volume:   307
Dimensions:   Width: 15.50cm , Height: 1.40cm , Length: 23.50cm
Weight:   0.580kg
ISBN:  

9783540298014


ISBN 10:   3540298010
Pages:   228
Publication Date:   09 May 2006
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

Structure and Replication of Hepatitis Delta Virus RNA.- HDV RNA Replication: Ancient Relic or Primer?.- HDV Ribozymes.- RNA Editing in Hepatitis Delta Virus.- Post-translational Modification of Delta Antigen of Hepatitis D Virus.- The Role of the HBV Envelope Proteins in the HDV Replication Cycle.- Prenylation of HDAg and Antiviral Drug Development.- Hepatitis Delta Virus Genetic Variability: From Genotypes I, II, III to Eight Major Clades?.- Functional and Clinical Significance of Hepatitis D Virus Genotype II Infection.- Immunology of HDV Infection.- The Woodchuck Model of HDV Infection.

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