Hepatitis C Virus: From Molecular Virology to Antiviral Therapy
Author:   Ralf Bartenschlager
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Edition:   2013 ed.
Volume:   369
ISBN:  

9783642273391


Pages:   346
Publication Date:   15 March 2013
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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Hepatitis C Virus: From Molecular Virology to Antiviral Therapy


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Overview

Hepatitis C virus (HCV), a major causative agent of chronic liver disease, is spread throughout the world and around 170 million people are persistently infected. In this volume, world-leading experts in the field of HCV research have compiled the most recent scientific advances to provide a comprehensive and very timely overview of the various facets of HCV. The book starts with a discussion of the possible origin of HCV and its spread among the human population. The focus of the subsequent chapters is on available cell culture and in vivo models before shifting to the molecular and cellular principles underlying the viral replication cycle. These chapters are complemented by insightful descriptions of the innate and adaptive immune responses to HCV as well as the virus-associated pathogenesis. Finally, the development of antiviral therapies, which is closely linked with progress in basic research, and the implementation of those therapies into present and future daily clinical practice are highlighted.

Full Product Details

Author:   Ralf Bartenschlager
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   2013 ed.
Volume:   369
Dimensions:   Width: 15.50cm , Height: 2.10cm , Length: 23.50cm
Weight:   6.565kg
ISBN:  

9783642273391


ISBN 10:   3642273394
Pages:   346
Publication Date:   15 March 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

The Origin of Hepatitis C Virus.- Cell Culture Systems for Hepatitis C Virus.- Animal Models for Hepatitis C.- Hepatitis C Virus Entry.- Hepatitis C Virus Proteins: From Structure to Function.- Hepatitis C Virus RNA Translation.- Hepatitis C Virus RNA Replication.- Virion Assembly and Release.- Innate Immune Responses to Hepatitis C Virus.- Adaptive Immune Responses in Hepatitis C Virus Infection.- Liver Injury and Disease Pathogenesis in Chronic Hepatitis C.- Hepatitis C Virus-Specific Directly Acting Antiviral Drugs.- Treatment of Chronic Hepatitis C: Current and Future.

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