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OverviewInsulin resistance (IR) and metabolic syndrome are associated with the pathogenesis and progression of non-alcoholic fatty liver disease (NAFLD). It encompasses a spectrum of hepatic pathology, ranging from simple steatosis in its most benign form (fatty liver), going through nonalcoholic steatohepatitis (NASH) in its intermediate form, until cirrhosis and hepatocellular carcinoma, its most advanced forms. This book presents current research on the background of fatty acid oxidation; hepatic steatosis and its progression to NASH and cirrhosis; fibrosis and myofibroblastic cells differentiation; methods of diagnosis; clinical features and laboratory tests and, finally, rodent NAFLD and NASH models. Full Product DetailsAuthor: Marcia Barbosa Aguila , Caroline Fernandes-Santos , Alessandra Da Rocha Pinheiro-Mulder , Tatiane Da Silva FariaPublisher: Nova Science Publishers Inc Imprint: Nova Science Publishers Inc Weight: 0.166kg ISBN: 9781612095288ISBN 10: 1612095283 Pages: 85 Publication Date: 20 October 2011 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: In Print ![]() This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsIntroduction; Triglyceride Storage Regulation in Hepatocytes; Impairment of Fatty Acid Oxidation; NAFLD & Its Progression to NASH & Cirrhosis; Steatosis; Inflammation; Fibrosis & Myofibroblastic Cell Differentiation; Methods of Diagnosis; Rodent NAFLD & NASH Models; Conclusions; Index.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |