Overview

These are the proceedings of the international symposium to honor Dr. Harold R. Roberts, held in Chapel Hill, North Carolina in April of 1999. The volume covers prions and viral transmissions, unexplained aspects of hemophilia and hemostasis, novel approaches to therapy, and inhibitor development in hemophilia patients.

Full Product Details

Author:   Dougald M. Monroe ,  Ulla Hedner ,  Maureane R. Hoffman ,  Claude Negrier
Publisher:   Springer Science+Business Media
Imprint:   Kluwer Academic/Plenum Publishers
Edition:   2001 ed.
Volume:   489
Dimensions:   Width: 17.80cm , Height: 1.90cm , Length: 25.40cm
Weight:   1.340kg
ISBN:  

9780306465215

ISBN 10:   0306465213
Pages:   182
Publication Date:   31 March 2001
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

I. Infectious Disease Risk.- 1. The Transfusion-Transmitted Viruses in Blood Transfusion.- II. Unexplained Aspects of Hemophilia and Hemostasis.- 2. Are Patients with Glanzmann Thrombasthenia and the Bernard-Soulier Syndrome Protected Against Atherosclerosis?.- 3. Factor V: Dr. Jeckyll and Mr. Hyde.- III. Novel Approaches to Therapy.- 4. Gene Therapy for Hemophilia B: AA V-Mediated Transfer of the Gene for Coagulation Factor IX to Human Muscle.- 5. Use of Prophylaxis to Prevent Complications of Hemophilia.- 6. Factor VIII Inhibitors.- 7. Use of High Dose Factor VIIa in Hemophilia Patients.- IV. Inhibitor Development in Hemophilia Patients.- 8. The Incidence of Inhibitors in Hemophilia A and the Induction of Immune Tolerance.- 9. Mechanisms of B-Cell Tolerance.- 10. Mechanisms of Unresponsiveness: T- and B-Cell Mediated Mechanisms of Anergy.- 11. CD4+ T Cells Specific for Factor VIII as a Target for Specific Suppression of Inhibitor Production.- 12. CD40L Pathway Blockade as an Approach to Immuno-therapy.- Abstracts.- Contributors.

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