Overview

In this issue of Hematology/Oncology Clinics, guest editors Drs. Nancy Berliner and Barbara A. Degar bring their considerable expertise to the topic of Hemophagocytic Syndromes. Top experts provide in-depth perspectives on these uncommon but potentially life-threatening disorders, including pathology of histiocytic disorders, genomic alterations in LCH, immunopathology of HLH, clinical characteristics and treatment of familial HLH, and much more. Contains 11 relevant, practice-oriented topics including clinical characteristics and treatment of histiocytic disorders in both children and adults; genetics of familial HLH; secondary HLH (including malignancy, infection); the role of hematopoietic cell transplant in pediatric and adult HLH; and more Provides in-depth clinical reviews on hemophagocytic syndromes, offering actionable insights for clinical practice Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews

Full Product Details

Author:   Nancy Berliner, MD (Brigham and Women's Hospital <br>Professor of Medicine <br>Harvard Medical School <br>Boston, MA) ,  Barbara A. Degar, MD (Medical Director, Inpatient Oncology, Boston Children's Hospital, Assistant Professor in Pediatrics, Harvard Medical School, Boston, MA, USA)
Publisher:   Elsevier Health Sciences
Imprint:   Churchill Livingstone
Weight:   0.480kg
ISBN:  

9780443347634

ISBN 10:   0443347638
Pages:   240
Publication Date:   16 July 2025
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Molecular Pathogenesis of the Histiocytic and Dendritic Cell Neoplasms Genomic Alterations in Langerhans Cell Histiocytosis Clinical Characteristics and Treatment of Histiocytic Disorders in Children Genetics of Familial Hemophagocytic Lymphohistiocytosis (HLH) Clinical Characteristics and Treatment of Familial Hemophagocytic Lymphohistiocytosis Recognizing and Managing Secondary Hemophagocytic Lymphohistiocytosis in Adults: A Practical Clinical Guide Macrophage Activation Syndrome: Not Just for Rheumatologists Anymore Immune Effector Cell-associated Hemophagocytic Lymphohistiocytosis-like Syndrome (IEC-HS) Role of Hematopoietic Cell Transplantation in Pediatric and Adult Hemophagocytic Lymphohistiocytosis-Remaining Unknowns and Challenges

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