Overview

The revolutionary discovery of Helicobacter pylori started a new era in the understanding and management of gastroduodenal diseases. H. pylori is associated with chronic gastritis, peptic ulcers, MALT lymphoma, the pathogenesis of gastric cancer and several extra-gastric diseases. The organism displays an enormous genetic diversity and some strains harbor numerous virulence factors. No vaccines are available yet and increased antibiotic resistance of the bacteria is of growing concern. Many questions about H. pylori pathogenesis, epidemiology, prophylaxis, and treatment remain to be answered. In addition, the role of non-pylori Helicobacter species is becoming a topic of considerable medical interest. This book highlights recent research and provides an up-to-date summary of current knowledge for microbiologists, clinicians, and advanced students working with Helicobacter. The contributors offer an outstanding collection of reviews on many aspects of Helicobacter research, including: microbiology * virulence factors * immunology * vaccine research * epidemiology * diseases associated with the infection * antibiotic resistance * treatment (including the use of non-antibiotic agents). As a major reference volume on Helicobacter pylori and how it impacts on public health worldwide, the book is essential reading for those with an interest in the microbiology of H. pylori and is recommended for all microbiology libraries.

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9781904455844

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