Heart Failure
Author:   Johann Bauersachs ,  Javed Butler ,  Peter Sandner
Publisher:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2017
Volume:   243
ISBN:  

9783319866734


Pages:   581
Publication Date:   12 May 2018
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Heart Failure


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Overview

This special issue of the Handbook of Experimental Pharmacology on Heart Failure covers the entire spectrum of the field, from the current understanding and definitions of heart failure, to epidemiology and the importance of co-morbidities, clinical trial design and biomarkers, as well as imaging technologies. The main focus of this book is to review current and emerging heart failure therapies and potential targets for treatment.

Full Product Details

Author:   Johann Bauersachs ,  Javed Butler ,  Peter Sandner
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2017
Volume:   243
Dimensions:   Width: 15.50cm , Height: 3.00cm , Length: 23.50cm
Weight:   8.832kg
ISBN:  

9783319866734


ISBN 10:   3319866737
Pages:   581
Publication Date:   12 May 2018
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Introduction.- Epidemiology.- Clinical trial design, endpoints and regulatory requirements. Biomarkers HFpEF/HFrEF. Imaging Technologies / MRI and Echo. Comorbidities in HF. Current Guideline based therapy of HFreF and HFpEF. New and Emerging Therapies and Targets. Ivabradine.- Beta3 agonists.- Novel MRAs.- pGCs and Natriuretic peptides.- sGC stimulators.- PDE’s.- Adenosin and A1 Agonists.- Myosin heavy chain / Troponin.- Stem cells.- Diuretics and Vasopressin.- GeneTherapy.- RNA-based therapies and micro RNAs.- Cardiac myosin activation using gene therapy.- Bendavia – mitochondrial therapies.- WNT signaling.- Anticoagulation therapy and NOACS in HF.- Potassium Binders.- Iron.           

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