Overview

This text reviews how heart cells communicate and impulse propagation under normal as well as under pathological conditions. The complexity of intercellular coupling and impulse propagation is discussed, providing the reader with a broad view of the importance of these processes and how they contribute to the generation of cardiac arrhythmias and heart failure.

Full Product Details

Author:   Walmor C. de Mello ,  M.J. Janse
Publisher:   Kluwer Academic Publishers
Imprint:   Kluwer Academic Publishers
Edition:   2002 ed.
Volume:   12
Dimensions:   Width: 15.50cm , Height: 2.60cm , Length: 23.50cm
Weight:   1.890kg
ISBN:  

9781402071829

ISBN 10:   1402071825
Pages:   470
Publication Date:   31 October 2002
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

1 The Cardiac Syncytium.An Overview.- 2 Connexin Interacting Proteins.- 3 Cardiovascular Connexins:Molecular Composition and Biochemical Regulation.- 4 Heteromultimeric Gap Junction Channels: A Connection with Cardiac Physiology and Pathology.- 5 Intercellular Calcium Signaling In The Cardiovascular System.- 6 Biophysics of Gap Junction Channels.- 7 Phosphorylation of Connexin43 and Regulation Of Cardiac Gap Junction.- 8 The Sinoatrial Node.Gap Junction Distribution And Impulse Propagation.- 9 Inward and Outward Currents and Cardiac Discontinuous Conduction.- 10 Cellular Electrical Uncoupling During Ischemia.- 11 Cell Coupling and Impulse Propagation In the Failing Heart: The Role of the Renin Angiotensin System.- 12 Gap Junctions and Connexin Expression in Human Heart Disease.- 13 Ionic Channels and Fibrillation.- 14 Gap Junctions, Cardiac Excitability and Clinical Arrhythmias.

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