Hazardous Reagent Substitution: A Pharmaceutical Perspective

Author:   Rakesh Kumar Sharma (University of Delhi, India) ,  Rakeshwar Bandichhor (Dr Reddy's Laboratories Ltd, India) ,  Rakesh Sharma (University of Delhi, India) ,  Rakesh Sharma (University of Delhi, India)
Publisher:   Royal Society of Chemistry
Volume:   Volume 52
ISBN:  

9781782620501


Pages:   194
Publication Date:   12 December 2017
Format:   Hardback
Availability:   In Print   Availability explained
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Hazardous Reagent Substitution: A Pharmaceutical Perspective


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Overview

In recent years, a significant amount of progress has been made using green chemistry in the synthesis of synthetically useful compounds and molecules by replacing hazardous chemicals with greener alternatives. However, there is still room for improvement, especially in the pharmaceutical sector where new drugs are being formulated. This book examines green approaches to overcoming hazardous organic transformations. Summarizing recent developments, the book features a detailed description of some of the high impact active pharmaceutical ingredients that have been developed considering green chemistry approaches. It explores the design, engineering and process development and the calculations to account for waste. The book includes strategies to further advance green approaches in the development of generic pharmaceutical industries and features novel, innovative approaches that promote waste-free organic synthesis. This book is of interest to industrialists working in pharmaceuticals and researchers working in green chemistry.

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Author:   Rakesh Kumar Sharma (University of Delhi, India) ,  Rakeshwar Bandichhor (Dr Reddy's Laboratories Ltd, India) ,  Rakesh Sharma (University of Delhi, India) ,  Rakesh Sharma (University of Delhi, India)
Publisher:   Royal Society of Chemistry
Imprint:   Royal Society of Chemistry
Volume:   Volume 52
Weight:   0.461kg
ISBN:  

9781782620501


ISBN 10:   1782620508
Pages:   194
Publication Date:   12 December 2017
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Introduction to Hazardous Reagent Substitution in the Pharmaceutical Industry; Recyclability of Reagents; Recoverable Polymer-supported DMAP Derivatives; Synthesis of Atorvastatin; Synthesis of Raloxifene; Synthesis of Montelukast; Development of a Safe, Scalable, Azide-free Synthesis of 1-Aryl-1H-tetrazoles Using Diformylhydrazine; New Directions from Academia

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Author Information

Rakesh Kumar Sharma is Professor and Coordinator of Green Chemistry Network Centre, University of Delhi, India. Rakeshwar Bandichhor is an Associate Director at Dr. Reddy's Laboratories, India.

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