Overview

Harnessing Host Immunity for Periodontal Health: Novel Strategies for Inflammation Control and Regeneration presents host modulation therapy as a cornerstone of modern periodontology. Moving beyond traditional antimicrobial approaches, the book emphasizes the pivotal role of the immune-inflammatory response in shaping disease progression and clinical outcomes. It explores molecular pathways, cytokines, matrix metalloproteinases, and osteoimmunology, while highlighting pharmacologic agents, biologics, and emerging regenerative strategies. Systemic interrelationships with diabetes, cardiovascular disease, and other conditions are addressed, framing periodontitis as a disease of both local and systemic significance. Designed for postgraduate students, clinicians, and researchers, this work provides a synthesis of foundational biology, therapeutic advances, and clinical application. It positions host modulation not as an adjunct, but as a central strategy in advancing precision periodontal care.

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