Overview

Volumes 7 and 8 of the Handbook were published in 1977. In Volume 7 methods for studying unconditioned and conditioned behavior were reviewed. Attention was given to both ethological methods and operant conditioning techniques as applied to some selected aspects of behavior. Genetic, developmental, and environmental factors influencing behavior were also discussed. In Volume 8, neurotransmitter systems, and in par­ ticular brain circuits, were discussed in relation to behavior and to the effects of psychoactive drugs on behavior. The coverage was not exhaus­ tive because of space limitations. The topics selected for review were, at the time, the focus of considerable experimental effort; they included homeostasis-motivated behaviors: sleep, locomotion, feeding, drinking, and sexual behavior. Brain dopamine systems were therefore discussed in depth, since they were already known to be centrally involved in motivated behaviors. Learning mechanisms and emotion were reviewed in the remaining chapters. In 1984 we initiated an update of behavioral pharmacology to review areas of progress within the same scope as the earlier volumes. This update continues in Volume 19. Among the contributions are several that represent important advances in analyzing behavior and the use of more sophisticated methods to define the effect of drugs on particular aspects of behavior. The chapters by Blundell on feeding and Miczek on aggres­ sion illustrate the sophistication of modern ethopharmacology.

Full Product Details

Author:   Leslie Iversen ,  Solomon H. Snyder ,  Solomon Snyder
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Dimensions:   Width: 17.80cm , Height: 3.40cm , Length: 25.40cm
Weight:   1.237kg
ISBN:  

9781461290179

ISBN 10:   1461290171
Pages:   642
Publication Date:   12 November 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

1 Conditioned Drug Effects.- 1. Introduction.- 2. Conditioned Drug Effects: Evidence and Explanations.- 3. Implications.- 4. References.- 2 Developmental Neuropharmacology: Clinical and Neurochemical Perspectives on the Regulation of Attention, Learning, and Movement.- 1. Clinical Phenomena and Research Design.- 2. Attention Deficit Disorder with Hyperactivity.- 3. Learning Disorders.- 4. Tourette’s Syndrome of Chronic, Multiple Tics.- 5. Overview.- 6. References.- 3 Structure, Process, and Mechanism: Case Studies in the Psychopharmacology of Feeding.- 1. Introduction.- 2. Control of Feeding: A First Look.- 3. Drugs and Food Intake.- 4. Interpretation of Pharmacological Action.- 5. Contextual and Temporal Dimensions of Behavior.- 6. Structure, Process, and Mechanism.- 7. Methodological Developments.- 8. Case Studies in the Pharmacological Analysis of Feeding.- 9. Control of Feeding: A Second Look.- 10. References.- 4 The Psychopharmacology of Aggression.- 1. Recent History of Psychopharmacological Aggression Research.- 2. Framework for the Behavioral Analysis of Aggression.- 3. Preclinical and Clinical Aggression Research.- 4. References.- 5 The Electrophysiological and Biochemical Pharmacology of the Mesolimbic and Mesocortical Dopamine Neurons.- 1. Introduction.- 2. Anatomy of Midbrain Dopamine Systems.- 3. Distinguishing between A9 and A10 Dopamine Systems.- 4. Identification and Characterization.- 5. Dopamine Neuron Function Regulation.- 6. Effects of Neurotransmitters on A10 Dopamine Neuron Activity.- 7. Summary.- 8. References.- 6 Psychopharmacology of Repeated Seizures: Possible Relevance to the Mechanism of Action of Electroconvulsive Therapy.- 1. Introduction.- 2. Functional Changes after Seizures.- 3. Biochemical Consequences of Seizures.- 4. NeuroendocrineMarkers of Neurotransmitter Changes Following Electroconvulsive Shock.- 5. Are Any Biochemical and Functional Changes Associated?.- 6. Can Biochemical or Behavioral Changes Be Associated with Antidepressant Action of Electroconvulsive Shock?.- 7. References.- 7 Psychopharmacology of Nicotine: Stimulus Effects and Receptor Mechanisms.- 1. Introduction.- 2. Nicotine as a Positive Reinforcer.- 3. Nicotine as an Aversive Stimulus.- 4. Discriminative Stimulus of Nicotine.- 5. Nicotine and Brain Mechanisms of Reward.- 6. General Conclusions.- 7. References.- 8 The Behavioral Effects of Opiates.- 1. Introduction.- 2. The Effects of Opiates on Pain.- 3. The Effects of Opiates on Reward.- 4. The Effects of Opiates on Cardiovascular Function.- 5. Other Effects of Opiates on Behavior.- 6. References.- 9 Neuropeptides and Memory.- 1. Neuropeptides.- 2. Conceptual and Methodological Considerations.- 3. Hypophyseal Peptides and Memory.- 4. Nonhypophyseal Peptides and Memory.- 5. Synthesis.- 6. References.- 10 The Actions of Neuroleptic Drugs on Appetitive Instrumental Behaviors.- 1. Introduction.- 2. Hypotheses on the Behavioral Actions of Neuroleptics.- 3. Evaluation of Experiments on Dopaminergic Involvement in Reinforcement.- 4. Incentive Explanation of Neuroleptic Actions.- 5. An Alternative Explanation of Dopamine Antagonist Effects on Operant Behavior.- 6. References.- 11 Second-Generation Antidepressants.- 1. Introduction.- 2. General Properties of Second-Generation Antidepressants.- 3. Methodological Approaches.- 4. Summary and Conclusions.- 5. References.

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