Overview

Full Product Details

Author:   Guy Healing (AstraZeneca, Cheshire, UK) ,  David Smith (AstraZeneca, Cheshire, UK) ,  D. Morton (University of Birmingham)
Publisher:   Taylor & Francis Ltd
Imprint:   Taylor & Francis Ltd
Dimensions:   Width: 15.60cm , Height: 2.10cm , Length: 23.40cm
Weight:   0.843kg
ISBN:  

9780748408672

ISBN 10:   0748408673
Pages:   344
Publication Date:   31 August 2000
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Introduction. Femoral Cannulation Using the Jacket/Harness Model in the Rat. Femoral Cannulation Using the Tail Cuff Exteriorisation Method in the Rat. Tethering and the Implanted Button Model in the Rat. Multidose Infusion Toxicity Studies in the Rat. Reproductive Infusion Toxicity Studies in the Rat. Femoral Cannulation Using the Tail Cuff Model in the Mouse. Multidose Infusion Toxicity Studies in the Mouse. Jugular Cannulation and Efficacy Studies in the Mouse. Femoral Cannulation of the Rabbit for Reproductive Toxicity Studies. Jugular Cannulation of the Rabbit for Reproductive Toxicity Studies. Jugular Cannulation of the Dog. The Non-Ambulatory Model in Dog Multidose Infusion Toxicity Studies. The Ambulatory Model in Dog Multidose Infusion Toxicity Studies. Surgical Preparation of the Large Primate. Multidose Infusion Toxicity Studies in the Large Primate. Surgical Preparation and Multidose Infusion Toxicity Studies in the Marmoset. Surgical Preparation of the Mini-Pig. Multidose Infusion Toxicity Studies in the Mini-Pig. Reproductive Toxicity Studies in the Mini-Pig. Common Pathological Findings in Continuous Infusion. The Use of Mini-Osmotic Pumps in Continuous Infusion Studies. The Contribution of Vehicles, Rates of Administration and Volumes to Infusion Studies. Equipment for Continuous Intravenous Infusion. NTI/Sales Copy

Reviews

...an excellent buy for anyone involved in drug development, risk assessment or within drug licensing agencies and in academic research. ...This book represents a benchmark achievement for this technique ...it will become the standard for many years to come British Toxicology Society Newsletter

an excellent buy for anyone involved in drug development, risk assessment or within drug licensing agencies and in academic research. This book represents a benchmark achievement for this technique it will become the standard for many years to come British Toxicology Society Newsletter

Author Information

Guy Healing, David Smith

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