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Author:   António Salgado (Principal Investigator, Life and Health Sciences Research Institute, Adjunct Associate Professor, School of Medicine, University of Minho, Braga, Portugal) ,  Antonio Salgado (Principal Investigator, Life and Health Sciences Research Institute, Adjunct Associate Professor, School of Medicine, University of Minho, Braga, Portugal) ,  Antonio Salgado (Principal Investigator, Life and Health Sciences Research Institute, Adjunct Associate Professor, School of Medicine, University of Minho, Braga, Portugal) ,  Antonio Salgado (Principal Investigator, Life and Health Sciences Research Institute, Adjunct Associate Professor, School of Medicine, University of Minho, Braga, Portugal)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Elsevier Science Publishing Co Inc
Weight:   1.110kg
ISBN:  

9780128180846

ISBN 10:   0128180846
Pages:   710
Publication Date:   08 June 2020
Audience:   College/higher education ,  Tertiary & Higher Education
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

1. Insights on Nervous System Biology and Anatomy 2. Introduction to Neurodegenerative Diseases 3. Introduction to Trauma in CNS 4. Impact of Neuro-inflammation in Injury and Disease in the CNS 5. Current Clinical Approaches in Neurodegenerative Diseases 6. Neuroprotection in the Injured Spinal Cord 7. Immunomodelatory Approaches for Tackling Neuro-Inflammation 8. Role of Fetal and Adult Tissues in CNS Regenerative Medicine 9. Adult Stem Cells' Therapeutic Potential for Injured CNS 10. iPSCs: An Essential Toolkit for Repair and Regeneration of the CNS? 11. Biomaterial-Based Systems as Biomimetic Agents in the Repair of the CNS 12. Tissue Engineering and Regenerative Medicine in CNS Repair 13. New Trends in Drug Delivery in CNS Regeneration 14. Gene Therapy Approaches in CNS Regenerative Medicine 15. Gene Editing and CNS Regeneration 16. Molecular Therapies in Neurodegeneration and Injury 17. Deep Brain Stimulation and Parkinson's Disease 18. Brain-Spinal Cord Interfaces 19. Electroceuticals 20. Secretome of Cells and Its Role in Neuroregeneration 21. 3D Organoids and Bioreactors 22. Microfluidics and Lab-on-a-Chip 23. Translational Research: From Proof of Concept to Clinical Trials 24. Advanced Therapies Medicinal Products 25. Animal Models of CNS Disorders 26. Bioethics in Translation Research and Clinical Trials

Reviews

The book's subject matter helps give readers context surrounding upcoming advances in the field of CNS regenerative medicine. The book will be useful to practitioners faced with answering difficult questions of those who have experienced a CNS injury, such as what is in the pipeline and/or what may be helpful in the future. The book also makes research concepts more accessible to students and residents to foster further research in these areas. --Doody Reviews

Author Information

Dr. António Salgado is a PrincipaI Investigator at the Life and Health Sciences Research Institute (ICVS) and an Adjunct Associate Professor in the School of Medicine, University of Minho. His research interests are focused on the development of innovative therapies for CNS repair, namely on Spinal Cord Injury and Parkinson’s Disease. His main areas of research are: 1) Development of ECM like hydrogels for the transplantation of Mesenchymal Stem Cells into the injured CNS; 2) Role of the secretome of MSCs in neuroprotection and repair, particularly the establishment of novel therapies based on the sole use of MSCs secretome.. Presently he is the coordinator of the Portuguese Network for Spinal Cord Injury Research and director of the Spinal Cord Injury Initiative @ ICVS (SCICVS). He serves as an Associate Editor for Biomed Research International, Biochimie, BMC Neuroscience and Stem Cells International. He has received several distinctions for his work including the Gulbenkian Award on Cutting Edge Research in Life Sciences, and the Prize Melo e Castro for Spinal Cord Injury Research, awarded by Santa Casa de Misericordia de Lisboa (2013 and 2017).

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