Overview

Hydroxyacetophenones constitute the starting material for a wide variety of syntheses in organic chemistry. They are versatile building blocks serving many different applications, such as specialty polymers, pharmaceuticals and fine chemicals. In this Handbook the diverse ways of obtaining over 3000 hydroxyacetophenones are described and their physico-chemical properties and spectroscopic data references are indicated. The Handbook is presented in dictionary style, with a logical classification of the ketones, making the information easily available for consultation. Ketones are classified methodically. They are thus easily accessible from three tables: This completely revised and enlarged edition includes: This Handbook is the reference on hydroxyacetophenones. It is a powerful synthesis tool for the researcher or industrial producers. Nowhere else are so many compounds covered or the physical properties and relevant syntheses provided. It provides a wide choice of hydroxyketones required to achieve syntheses based upon this range of intermediates.

Full Product Details

Author:   Robert Martin
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2nd Enlarged edition
Dimensions:   Width: 16.00cm , Height: 6.40cm , Length: 24.00cm
Weight:   2.114kg
ISBN:  

9781402022906

ISBN 10:   1402022905
Pages:   1136
Publication Date:   23 February 2005
Audience:   College/higher education ,  Professional and scholarly ,  Tertiary & Higher Education ,  Professional & Vocational
Replaced By:   9781402097867
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

Foreword Introduction VOLUME I: MONOKETONES UNSUBSTITUTED ON THE ACETYL GROUPS Chapter 1. Compounds derived from acetic acid: Molecular Formula Index Chemical Abstracts Registry Numbers Usual Names Index Common Abbreviations VOLUME II: MONOKETONES SUBSTITUTED ON THE ACETYL GROUPS Chapter 2. Compounds derived from halogenoacetic acids: 2.1. Compounds derived from bromoacetic acids 2.2. Compounds derived from chloroacetic acids 2.3. Compounds derived from fluoroacetic acids 2.4. Compounds derived from iodoacetic acids Chapter 3. Compounds derived from aminoacetic acids 3.1. Compounds derived from aminoacetic acid 3.2. Compounds derived from substituted aminoacetic acids Chapter 4. Compounds derived from alkoxyacetic acids 4.1. Compounds derived from methoxyacetic acids 4.2. Compounds derived from phenylmethoxyacetic acids 4.3. Compounds derived from ethoxyacetic acids 4.4. Miscellaneous Chapter 5. Compounds derived from aryloxyacetic acids 5.1. Compounds derived from phenoxyacetic acid 5.2. Compounds derived from substituted phenoxyacetic acids Chapter 6. Compounds derived from hydroxyacetic acids Chapter 7. Compounds derived from acyloxy- and aroyloxyacetic acids 7.1. Compounds derived from acetoxyacetic acids 7.2. Compounds derived from other acyloxy- and phenacyloxyacetic acids 7.3. Compounds derived from benzoyloxyacetic acids Chapter 8. Compounds derived from nitroacetic acids Chapter 9. Compounds derived from arylacetic acids 9.1. Compounds derived from phenylacetic acid 9.2. Compounds derived from substituted phenylacetic acids 9.3. Compounds derived from di- and triphenylacetic acids 9.4. Compounds derived from cycloalkylacetic acids Chapter 10. Compounds derived from S-substituted mercaptoacetic acids Chapter 11. Aromatic ketones containing only acetyl groups 11.1. Acetyl groups located on one ring 11.2. Acetyl groups located on different rings Chapter 12. Aromatic polyketones containing at least one acetyl group and one other acyl group 12.1. Acyl groups located on one ring 12.2. Acyl groups located on different rings REFERENCES MOLECULAR FORMULA INDEX CHEMICAL ABSTRACTS REGISTRY NUMBERS USUAL NAMES INDEX COMMON ABBREVIATIONS

Reviews

From the Foreword... When Dr Martin asked me to write a Foreword for his new handbook, I was really enthusiastic. Indeed I met Dr Martin for the first time when joining the Institute Curie at the beginning of the 1990's to take the direction of the team of medicinal chemists. At that time Dr Martin was retired from the Sanofi company but was working at the bench from early in the morning to late in the evening like a young and brilliant student. He devoted all his time and energy to make complete the description of what constitutes the subject of his published handbooks. Tireless reader of a huge lot of periodicals, he collected, day after day, a large amount of data about the hydroxyacetophenones and the hydroxybenzophenones. As a continuation of this already published two handbooks of both classes of compounds, Dr Martin now takes care of substituted hydroxyacetophenones. As these new collected compounds have been added to the unsubstituted analogs, one can say that this book constitutes and enlarged second edition of the first hydroxyacetophenone handbook. Not less than 3000 molecules and 3500 references can be found in this new volume. The presentation is the same as in the first two volumes with consistent data on the synthetic route or on the natural origin or each compound, and their physicochemical and spectroscopic characteristics available in the literature. I am sure that, even at the internet era, this handbook will be helpful for the readers concerned by the use of these compounds in all the aspects of chemistry covering pharmaceutical, agrochemical, perfume, plastic preservatives domains or elaboration of small libraries of organic compounds for biological screening. Besides, consulting such a handbook is greatly facilitated by the presence of three comprehensive tables, including CAS number, official nomenclature and usual names. This will be helpful to the reader and I am sure that this book will meet the success it deserves. Claude Monneret, Research Director at the CNRS

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