Overview

"The Handbook of Glycomics provides the first comprehensive overview of the emerging field of glycomics, defined as the study of all complex carbohydrates in an organism or cell (""the glycome""). Beginning with analytic approaches and bioinformatics, this work provides a detailed discussion of relevant databases, data integration, and analysis. It then moves on to a discussion of specific model organism and pathogen glycomes followed by therapeutic approaches to human disorders of glycosylization. Structure and function of glycomes are included along with state-of-the-art technologies and systems approaches to the analysis of glycans."

Full Product Details

Author:   Richard D. Cummings (Emory University School of Medicine, Atlanta, GA, USA) ,  J. Michael Pierce (University of Georgia, Athens, USA)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Dimensions:   Width: 18.40cm , Height: 3.30cm , Length: 26.00cm
Weight:   1.290kg
ISBN:  

9780123736000

ISBN 10:   0123736005
Pages:   512
Publication Date:   19 October 2009
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Introduction to Glycomics SECTION 1: Glycoconjugate Structural Analysis 1. Glycoproteomics: N-glycan Analysis 2. Glycoproteomics: O-glycan Analysis 3. Glycosaminoglycans 4. Isotopic Labeling of Glycans for Quantitative Glycomics SECTION II: Glycotranscriptomics 5. Glycotranscriptomics SECTION III: Protein-Glycan Interactions 6. Glycan Arrays 7. Chromatographic and Mass Spectrometric Techniques SECTION IV: Glycobioinformatics 8. Integration of Glycomics Knowledge and Data 9. KEGG GLYCAN for integrated analysis of pathways, genes, and glycan structures 10. European Glycomics Portal SECTION V: Glycomes 11. Glycomics of the Immune System 12. Mouse and Human 13. Drosophila 14. Malaria 15. Parasitic Worms SECTION VI: Disease Glycomes 16. Cancer Glycomics 17. An Introduction to Human Disorders of Glycosylation 18. Summary

Reviews

Overall, this book is well presented; each chapter contains very valuable figures, an up-to-date bibliography, and tables and charts including 22 color plates at the end of the book. The subject index is useful for fast orientation in the numerous topics discussed in the book. A remarkable feature of this book is very wide range of high_ lighting scientific directions that currently unite in glycomics. This book will no doubt serve as an excellent comprehensive overview and will be handy reference book for scientists and teachers in glycobiology, biochemistry, molecular biology, biotechnology, and medicine. --Biochemistry 2010, Volume 75. No. 8, pp. 1064-65

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