Overview
Truly global in scope and with contributions from leading researchers around the world, The Handbook of Cannabis is the definitive resource on this fascinating drug. Combining scientific perspectives and clinical applications, it covers a vast array of topics, from why over the centuries cannabis has been used as a medicine, through the regulations facing those wishing to self-administer cannabis or provide cannabis-based medicines, to the chemical structure of its many constituents and the rapidly growing group of synthetic cannabinoids that are currently being used for 'legal highs'.With each chapter written by a group of one or more internationally recognised subject experts, it provides academics and researchers with authoritative scientific material on the main pharmacological actions and their effects, as well as their pharmacokinetics, metabolism, and forensic detection. In addition it also examines the complex morphology, cultivation, harvesting, and processing of cannabis and the ways in which the plant's chemical composition can be controlled.As well as offering a raft of scientific information there is extensive coverage of cannabinoid-based medicines. Helping readers to identify and evaluate their benefits, chapters explore pharmacological actions and the effects that seem to underlie approved therapeutic uses, how they are currently used to treat certain disorders, and the ever-growing number of wide-ranging potential clinical applications. There is also coverage of both the legal and illegal sources of cannabis, including 'coffee shops' and 'cannabis dispensaries'.The complex issue of 'recreational cannabis' is also tackled. The sought-after and adverse psychological and non-psychological effects are described and discussions are included on how some adverse effects can be lessened by at least one constituent of cannabis, and that it might be possible to reduce the harm that cannabis does to some by changing current regulatory policies. The Handbook of Cannabis is a one-stop reference; essential reading for all clinicians, pharmacologists, psychologists, and psychiatrists interested in this drug, as well as those working in the field of public health.
Full Product Details
Author: Roger Pertwee (Professor of Neuropharmacology, Professor of Neuropharmacology, School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, UK)
Publisher: Oxford University Press
Imprint: Oxford University Press
Dimensions:
Width: 17.10cm
, Height: 4.00cm
, Length: 24.70cm
Weight: 1.294kg
ISBN: 9780198792604
ISBN 10: 0198792603
Pages: 784
Publication Date: 04 August 2016
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Paperback
Publisher's Status: Active
Availability: To order 
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Table of Contents
Part 1 Constituents, History, International Control, Cultivation and Phenotypes of CannabisEthan B. Russo: 1: Mahmoud A. ElSohly and Waseem Gul: Constituents of Cannabis Sativa 2: Ethan B. Russo: The Pharmacological History of Cannabis 3: Alice P. Mead: International Control of Cannabis 4: David J. Potter: Cannabis Horticulture 5: Etienne de Meijer: Cannabis Phenotypes (Chemotypes) of Cannabis Part 2 Pharmacology, Pharmacokinetics, Metabolism and ForensicsRoger G. Pertwee: 6: Roger G. Pertwee and Maria Grazia Cascio: Known Pharmacological Actions of Delta-9-Tetrahydrocannabinol and of Four Other Chemical Constituents of Cannabis that Activate Cannabinoid Receptors 7: Maria Grazia Cascio and Roger G. Pertwee: Known Pharmacological Actions of Nine Non-Psychotropic Phytocannabinoids 8: Bela Szabo: Effects of Phytocannabinoids on Neurotransmission in the Central and Peripheral Nervous Systems 9: Eliot L. Gardner: Cannabinoids and Addiction 10: Sachin Patel, Matthew N. Hill, and Cecilia J. Hillard.: Effects of Phytocannabinoids on Anxiety, Mood, and the Endocrine System 11: Saoirse E. O'Sullivan: Phytocannabinoids and the Cardiovascular System 12: Marnie Duncan and Angelo A. Izzo: Phytocannabinoids and the Gastrointestinal System 13: Jordyn M. Stuart, Emma Leishman, and Heather B. Bradshaw: Reproduction and Cannabinoids: Ups and Downs, Ins and Outs 14: Guy A. Cabral, Erinn S. Raborn, and Gabriela A. Ferreira: Phytocannabinoids and the Immune System 15: John M. McPartland and Ethan B. Russo: Non-Phytocannabinoid Constituents of Cannabis and Herbal Synergy 16: Marilyn A. Huestis and Michael L. Smith: Cannabinoid Pharmacokinetics and Disposition in Alternative Matrices Part 3 Medicinal Cannabis and Cannabinoids: Clinical DataEthan B. Russo: 17: Arno Hazekamp and George Pappas: Self-Medication with Cannabis 18: Amanda Reiman: Cannabis Distribution: Coffee Shops to Dispensaries 19: Alison Thompson and Verity Langfield: Development of Cannabis-Based Medicines: Regulatory Hurdles/Routes in Europe and the United States 20: Stephen Wright and Geoffrey Guy: Licensed Cannabis-Based Medicines: Benefits and Risks 21: Mark A. Ware: Synthetic Psychoactive Cannabinoids Licensed as Medicines 22: William Notcutt and Emily L. Clarke: Cannabinoids in Clinical Practice: A UK Perspective Part 4 Approved Therapeutic Targets for Phytocannabinoids: Preclinical PharmacologyMarnie Duncan: 23: Erin M. Rock, Martin A. Sticht, and Linda A. Parker: Effect of Phytocannabinoids on Nausea and Vomiting 24: Luigia Cristino and Vincenzo Di Marzo: Established and Emerging Concepts of Cannabinoid Action on Food Intake and their Potential Application to the Treatment of Anorexia and Cachexia 25: Barbara Costa and Francesca Comelli: Pain 26: Gareth Pryce and David Baker: Cannabis and Multiple Sclerosis Part 5 Some Potential Theraputic Targets for PhytocannabinoidsMarnie Duncan: 27: Javier Fernández-Ruiz, Eva de Lago, María Gómez-Ruiz, Concepción García, Onintza Sagredo, and Moisés García-Arencibia: Neurodegenerative Disorders Other Than Multiple Sclerosis 28: Daniela Parolaro, Erica Zamberletti and Tiziana Rubino: Cannabidiol/Phytocaanabinoids: A New Opportunity for Schizophrenia Treatment 29: Eric Murillo-Rodríguez, Lisa Aguilar-Turton, Stephanie Mijangos-Moreno, Andrea Sarro-Ramírez, and Óscar Arias-Carrión: Phytocannabinoids as Novel Therapeutic Agents for Sleep Disorders 30: Claire M. Williams, Nicholas A. Jones and Benjamin J. Whalley: Cannabis and Epilepsy 31: Pál Pacher and George Kunos: Cardiovascular, Metabolic, Liver, Kidney, and Inflammatory Disorders 32: Sergio Oddi and Mauro Maccarrone: Phytocannabinoids and Skin Disorders 33: Heping Xu and Augusto Azuara-Blanco: Phytocannabinoids in Degenerative and Inflammatory Retinal Diseases: Glaucoma, Age-Related Macular Degeneration, Diabetic Retinopathy and Uveoretinitis 34: Itai Bab: Bone As a Target for Cannabinoid Therapy 35: Guillermo Velasco, Cristina Sánchez, and Manuel Guzmán: Cancer Part 6 Recreational Cannabis: Sought-After Effects, Adverse Effects, Designer Drugs and Harm MinimizationWayne Hall: 36: H. Valerie Curran and Celia J. A. Morgan: Desired and Undesired Effects of Cannabis on the Human Mind and Psychological Well-Being 37: Paul D. Morrison, Sagnik Bhattacharyya, and Robin M. Murray: Recreational Cannabis: The Risk of Schizophrenia 38: Franjo Grotenhermen: Nonpsychological Adverse Effects 39: Wayne Hall and Louisa Degenhardt: Harm Reduction Policies for Cannabis 40: Brian F. Thomas, Jenny L. Wiley, Gerald T. Pollard, and Megan Grabenauer: Cannabinoid Designer Drugs: Effects and Forensics
Reviews
`It provides a detailed review of a wide variety of areas related to this compound, from historical use, pharmacological actions of this substance, the scientific evidence supporting its medicinal properties, as well as the political and legal issues around its medical and recreational uses. Overall this is an excellent reference for a wide variety of individuals that would be a welcome addition to most libraries.' Doody's Notes The Handbook of Cannabis is clearly a labour of love. Prof. Pertwee is an international leading light in the study of cannabis and cannabinoids. He has recruited an extended list of contributors and sub-editors, who have managed a Herculean task of summarising the wealth and breadth of knowledge on cannabis and cannabinoids. This handbook will be a fantastic reference book for both researchers and those outside the area to obtain an authoritative summary on that topic. This book is a masterpiece! The contributions Roger Pertwee has made (namely his research on experimental multiple sclerosis and cannabinoids) are incredibly noteworthy. The Handbook of Cannabis contains contributions from many important international researchers, and I am delighted to commend the handbook, which will no doubt be a landmark in the field.
It provides a detailed review of a wide variety of areas related to this compound, from historical use, pharmacological actions of this substance, the scientific evidence supporting its medicinal properties, as well as the political and legal issues around its medical and recreational uses. Overall this is an excellent reference for a wide variety of individuals that would be a welcome addition to most libraries. Doody's Notes The Handbook of Cannabis is clearly a labour of love. Prof. Pertwee is an international leading light in the study of cannabis and cannabinoids. He has recruited an extended list of contributors and sub-editors, who have managed a Herculean task of summarising the wealth and breadth of knowledge on cannabis and cannabinoids. This handbook will be a fantastic reference book for both researchers and those outside the area to obtain an authoritative summary on that topic. This book is a masterpiece! The contributions Roger Pertwee has made (namely his research on experimental multiple sclerosis and cannabinoids) are incredibly noteworthy. The Handbook of Cannabis contains contributions from many important international researchers, and I am delighted to commend the handbook, which will no doubt be a landmark in the field.
Author Information
Roger Pertwee has three degrees from the University of Oxford: MA (in biochemistry), D.Phil. (in pharmacology) and D.Sc. (in physiological sciences). He is Professor of Neuropharmacology at the University of Aberdeen, Director of Pharmacology for GW Pharmaceuticals, co-chairman of the International Union of Basic and Clinical Pharmacology (IUPHAR) Subcommittee on Cannabinoid Receptors, a co-ordinator of the British Pharmacological Society's Special Interest Group on Cannabinoids, and visiting Professor at the University of Hertfordshire. He has also served as chairman of the International Association for Cannabinoid Medicines (IACM; 2005-2007) and twice as President of the International Cannabinoid Research Society (ICRS; 1997-1998; 2007-2008), and is currently ICRS International Secretary and also a member of the IACM board of directors.
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