Overview

This is a comprehensive tool covering all manifestations of antimicrobial resistance, with viral, bacterial, parasitical and fungal resistance each given a dedicated section. The underlining molecular mechanisms, which depend not only on the microbe, but on the specific drug (target), are highly diverse, and are covered in great detail. This work also discusses and compares the biological, biochemical and structural aspects of resistance and its evolution.​

Full Product Details

Author:   Matthias Gotte ,  Albert Berghuis ,  Greg Matlashewski ,  Donald Sheppard
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   1st ed. 2017
Dimensions:   Width: 15.50cm , Height: 3.90cm , Length: 23.50cm
Weight:   1.379kg
ISBN:  

9781493906932

ISBN 10:   1493906933
Pages:   606
Publication Date:   25 March 2017
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Bacteria.- Origins of antibiotic resistance (Resistome).- Dissemination of antibiotic resistance.- Mechanisms of antibiotic resistance.-Strategies for combating antibiotic resistance.- Multiple-drug-resistant bacteria.- Resistant Tuberculosis.- MRSA.- Fungi.- Microevolution of drug resistance.- Environmental induction of azole resistance in medical molds.- Echinocandin resistance in medically relevant fungi.- Role of drug efflux in azole resistance.- Parasites.- Drug-resistant Leishmania.- Drug resistance in Helminth infections.- Drug resistance in Malaria.- Drug resistance in schistosome infections.- Drug resistance in trypanosome infections.- HIV.- Resistance to RT inhibitors.- Resistance to Integrase Inhibitors.- Resistance to Entry inhibitors.- Resistance Testing.- Virology.- Resistance to viral protease inhibitors: The substrate envelope.- Resistance to new Direct-Acting-Antivirals against HCV.- HBV Resistance.- Resistance to antiherpetic drugs.- Influenza Resistance.

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Author Information

Matthias Gotte, Department of Medical Microbiology and Immunology, University of Alberta, Canada Albert M. Berguis, Department of Biochemistry, McGill University, Canada Greg Matlashewski, Department of Microbiology and Immunology, McGill University, Canada Donald Sheppard, Department of Microbiology and Immunology, McGill University, Canada Mark A. Wainberg, Department of Microbiology and Immunology, McGill University, Canada

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