Overview

Acid-base indicators (pH indicators) are substances (dyes) that change their color with a change in pH. There is no book available in the market directly on acid-base indicators, even though the use of acid-base indicators is widespread, growing rapidly, and has exploded recently. This updated handbook serves as a systematic and up-to-date library of information on 250+ acid-base indicators and as a practical guide for both chemists and non-chemists in industry and academia. Entries in this book are listed alphabetically and include eneral chmical name, chemical structure, other names, CA index name, CAS registry number, color index number, colour index name, Merck index number (The Merck Index, 15th Edition, 2013), chemical/dye class, molecular formula, molecular weight, physical form, solubility, melting point, boiling point, boiling point (calcd.), pH range, color-change at pH, pKa, pKa (calcd.), absorption (λmax), emission (λmax), molar extinction coefficient, quantum yield, synthesis, biological/medical applications, industrial applications, safety/toxicity, certification/approval and references Numerous recent references as well as original references (when reported) have been provided on various synthetic methods, biological/medical applications, industrial applications, and safety/toxicity data. This is the first ever book which provides safety/toxicity data with reference to acute toxicity, algal toxicity, amyloid toxicity, aquatic toxicity, bacterial toxicity, carcinogenicity, cardiotoxicity, cardiovascular toxicity, chromosomal aberrations, chronic toxicity, clastogenicity, cytotoxicity, developmental toxicity, DNA damage, ecotoxicity, embryotoxicity, endocrine disrupters, environmental toxicity, fish toxicity, genotoxicity, hematotoxicity, hepatocarcinogenicity, hepatotoxicity, immunotoxicity, membrane toxicity, microbial toxicity, mitochondrial toxicity, mutagenicity, nephrotoxicity, neurotoxicity, nucleic acid damage, ophthalmic toxicity, oral toxicity, ototoxicity, ovarian toxicity, photodynamic toxicity, photogenotoxicity, phototoxicity, phytotoxicity, pulmonary toxicity, reproductive toxicity, skin toxicity, subchronic toxicity, teratogenicity, tumorigenicity, vascular toxicity, and so on. The second edition of Handbook of Acid-Base Indicators (pH Indicators) has been revised, enlarged and updated with several recent references and added 53 new acid-base indicators. Further, the First Edition provides major applications of acid-base indicators, whereas the Second Edition provides biological/medical applications and industrial applications separately. The Second Edition also provides Certification by Biological Stain Commission (BSC) and Approval by Food & Drugs Administration (FDA) of acid-base indicators, wherever applicable. In addition, several appendixes have been provided at the end of the book for scientists to conveniently and easily find an acid-base indicator as per their need. These appendixes include CAS Registry Numbers, Colour Index Names and Colour Index Numbers, Acridines, Anthraquinones, Aromatics, Azo, Benzeins, Coumarins, Fluorescent, Hydrazines, Maleins, Miscellaneous, Naphthalenes, Nitro, Phenolnaphthaleins, Phthaleins, Quinolines, Sulfonephthaleins, Triphenylmethanes, and Xanthenes.

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9781138198050

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Ram W. Sabnis is an accomplished Intellectual Property Manager at Arclin USA LLC, where he oversees the company’s global patent portfolio and collaborates with outside counsel on trademark matters. He drafts and prosecutes U.S. and PCT international patent applications, engages closely with inventors and examiners, and supports merger and acquisition activities through in‑depth patent portfolio reviews. With more than 35 years of combined technical and legal experience following his Ph.D., Dr. Sabnis brings a rare dual expertise that bridges industrial research and development (over 16 years) and patent law practice (over 19 years) across both law firm and corporate environments. His professional interests span a broad spectrum of scientific and technological disciplines, including dyes and pigments, organic and medicinal chemistry, heterocycles, polymers, coatings, material science, synthesis, formulations, and patents. Dr. Sabnis has held prior roles with leading corporations and law firms, including Georgia‑Pacific LLC, Pfizer Inc., Squire Patton Boggs LLP, and Smith Gambrell Russell LLP, where he drafted and prosecuted high‑value patent applications. His scientific career is equally distinguished, marked by 500+ publications, including 3 books. Born and raised in Mumbai, India, Dr. Sabnis earned his M.Sc. in Organic Chemistry from the University of Mumbai and his Ph.D. in Organic Chemistry (Dyes) from the Institute of Chemical Technology (ICT, formerly UDCT), Mumbai. He is a Chartered Colorist, a Fellow of the Society of Dyers and Colourists (CCol FSDC), and a Fellow of the Royal Society of Chemistry (FRSC). Internationally recognized as one of the foremost authorities on dye chemistry, Dr. Sabnis is credited with inventing the world’s first non‑staining colored bubbles and a color‑changing dye system with wide‑ranging commercial and scientific applications. Over the past four decades, he has made significant contributions to color science, advancing dyes for biomedical, personal care, cosmetic, electronic (display/OLED), ink, paint, plastic, textile, and toy applications. Dr. Sabnis has over 500 publications, including books, book chapters, encyclopaedia entries, reviews, patents, journal papers and symposia papers. He is an inventor on numerous U.S. Patents and PCT international applications and has received several prestigious honors such as the Perkin Innovation Award, Pfish Award, Grand Innovation Award, Competitive Spirit Award, and Best Doctoral Thesis Award. The Society of Dyers and Colourists (Bradford, U.K.) has recognized him with the Gold Medal for Outstanding Service to the Coloration Industry and the Centenary Medal for Best Review in Coloration Technology. He has also received the UAA‑ICT Distinguished Alumnus Award ‑ Research from his alma mater, the Institute of Chemical Technology (ICT). He has been recognized for both professional excellence and community impact. He has been honoured with USPTO Patent Pro Bono Achievement Certificates (2021–2025) and has represented approximately 400 patent matters, including U.S. Patents and PCT international applications. The American Chemical Society (ACS) has awarded him Certificates of Appreciation for his exceptional service to the U.S. National Chemistry Olympiad (USNCO) (2023‑2025). He has also been bestowed with 2025 Outreach Volunteer of the Year Award by the American Chemical Society (2025). Further, he serves as an ACS Patent Panellist for ACS Medicinal Chemistry Letters and as an Advisory Board member for Georgia Patents. In addition to his legal practice, Dr. Sabnis is deeply committed to education. He serves as an Adjunct Professor at the Institute of Chemical Technology (ICT), Mumbai (2019‑Present) and was an Adjunct Assistant Professor at the University of Missouri, Rolla (1999‑2004). Dr. Sabnis is the author of three authoritative reference continues to pursue his lifelong passion for the chemistry works on color chemistry: Handbook of Fluorescent of color while advancing innovation at the intersection Dyes and Probes, Handbook of Biological Dyes and of science and intellectual property.

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