Glycosylation and Cancer

Author:   Richard R Drake (Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, USA) ,  Lauren Ball (Cell and Molecular Pharmacolgy & Experimental Therapeutics, Medical University of South Carolina,USA)
Publisher:   Elsevier Science Publishing Co Inc
Volume:   126
ISBN:  

9780128013816


Pages:   418
Publication Date:   04 March 2015
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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Glycosylation and Cancer


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Overview

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics.

Full Product Details

Author:   Richard R Drake (Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, USA) ,  Lauren Ball (Cell and Molecular Pharmacolgy & Experimental Therapeutics, Medical University of South Carolina,USA)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Volume:   126
Dimensions:   Width: 15.20cm , Height: 2.80cm , Length: 22.90cm
Weight:   0.790kg
ISBN:  

9780128013816


ISBN 10:   0128013818
Pages:   418
Publication Date:   04 March 2015
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. Glycosylation and Cancer: Moving Glycomics to the Forefront Richard R. Drake 2. Role of N-glycans in cancer Biomarker, Progression and Metastasis, and Therapeutics    Naoyuki Taniguchi  and Yasuhiko Kizuka 3. Simple Sugars to Complex Disease – Mucin-type O-glycans in Cancer Matthew R. Kudelka, Tongzhong Ju, Jamie Heimburg-Molinaro, and Richard D. Cummings 4. Intracellular Protein O-GlcNAc Modification Integrates Nutrient Status with Transcriptional and Metabolic Regulation Alexis K. Nagel and Lauren E. Ball 5. The Detection and Discovery of Glycan Motifs in Biological Samples Using Lectins and Antibodies: New Methods and Opportunities Huiyuan Tang, Peter Hsueh, Doron Kletter, Marshall Bern, and Brian Haab 6. Glycosylation Characteristics of Colorectal Cancer Stephanie Holst, Manfred Wuhrer and Yoann Rombouts 7. Glycosylation and Liver Cancer Anand Mehta, Harmin Herrera and Timothy Block 8. Functional Impact of Tumor-Specific N-linked Glycan Changes in Breast and Ovarian Cancers Huabei Guo and Karen Abbott 9. Glycosylation Alterations in Lung and Brain Cancer Hassan Lemjabbar-Alaoui, Andrew McKinney, Yi-Wei Yang, Vy M. Tran and  Joanna J. Phillip 10. Altered Glycosylation in Prostate Cancer Richard R. Drake, E. Ellen Jones, Thomas W. Powers and Julius O. Nyalwidhe

Reviews

"Praise for the Serial ""This classic and essential series presents critical overviews on select aspects of both cancer research and the basic underlying sciences."" --American Scientist ""Excellent, highly informative, in-depth reviews…expertly written, up-to-date, and well-referenced."" --Journal of Medicinal Chemistry ""This is a series that has a long tradition of excellence in the field of cancer biology."" --Doody’s Publishing Reviews"


Praise for the Serial This classic and essential series presents critical overviews on select aspects of both cancer research and the basic underlying sciences. -AMERICAN SCIENTIST Excellent, highly informative, in-depth reviews.expertly written, up-to-date, and well-referenced. -JOURNAL OF MEDICINAL CHEMISTRY This is a series that has a long tradition of excellence in the field of cancer biology. -DOODY'S PUBLISHING REVIEWS


Author Information

Dr. Drake is a Professor in the Department of Cell and Molecular Pharmacology and Experimental Therapeutics at the Medical University of South Carolina and SmartState Endowed Chair in Proteomics. He is an experienced protein biochemist and glycobiologist, with particular expertise in tumor biology and biomarker discovery from clinical fluids and tissues related to urological cancers and other cancers. He obtained his Ph.D. in Biochemistry at the University of Kentucky with Boyd Haley, generating multiple nucleotide sugar photoaffinity analogs for use in the study of glycosyltransferases. More extensive glycobiology training was done in post-doctoral work with Alan Elbein, and he began his academic career in Dr. Elbein’s department at the University of Arkansas for Medical Sciences. Currently, his research focus is on direct analysis of glycans and glycolipids in tissues using state-of-the-art MALDI mass spectrometry imaging approaches. Complementary glycopeptide mass spectrometry and metabolic labeling targeted approaches are being done to identify specific glycoproteins involved in the epithelial-to-mesenchymal transition.

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