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OverviewInitially believed to be inactive molecules, glycans are now considered essential for life, both under normal and pathological conditions. This volume of the series “Biology of Extracellular Matrix” reviews the most recent findings on the role of glycans in the development of diseases and the possible therapeutic use of this class of molecules. It shows how the interaction of glycans with growth factors, growth factor binding proteins, extracellular proteases, protease inhibitors, chemokines, morphogens, and adhesive proteins regulates inflammation, infection, cancer, atherosclerosis, thrombosis and embryonic stem cell biology. Furthermore, an extensive survey about the structure and pharmacological effects of unique marine glycosaminoglycans is discussed as well as the possibility of using these glycans as therapeutic agents. Full Product DetailsAuthor: Mauro S.G. PavãoPublisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K Edition: 2011 ed. Dimensions: Width: 15.50cm , Height: 1.80cm , Length: 23.50cm Weight: 0.471kg ISBN: 9783642168321ISBN 10: 3642168329 Pages: 188 Publication Date: 20 April 2011 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print ![]() This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsHeparan Sulfate Proteoglycan in Inflammation and Angiogenesis.- Heparan Sulfate Proteoglycans in Infection.- Glycans in cancer.- Glycosaminoglycans in atherosclerosis and thrombosis.- Glycans in Embryonic Stem Cells.- Heparan sulfate proteoglycans in cancer progression and therapy.- Structure and biological activities of glycosaminoglycan analogs from marine invertebrates: new therapeutic agents?.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |